Skip to main content
Fig. 1 | Thrombosis Journal

Fig. 1

From: Collagen-dependent platelet dysfunction and its relevance to either mitochondrial ROS or cytosolic superoxide generation: a question about the quality and functional competence of long-stored platelets

Fig. 1

Exaggerated Intra-platelet ROS generation in 5 days-stored PCs. a, b, d and e show the representative histograms and dot plots illustrating the expressions of DHR123 and DHE respectively detected in FL1 and FL2. Graph (c) shows significant increase of mitochondrial ROS in both CCCP induced (p < 0.01) and 5-days stored platelets (p < 0.01; analyzed by Kruskal-Wallis test with Dunn’s multiple comparison) with not significant (ns) difference between them (assessed by Mann–Whitney U test). Graph (f) shows significant increase of Superoxide in both PMA induced (p = 0.045) and 5-days stored platelets (p < 0.05; analyzed by Kruskal-Wallis test with Dunn’s multiple comparison) with significant (p = 0.048) difference between them (assessed by Mann–Whitney U test). Note: PCs; platelets concentrated, **p < 0.01, *p < 0.05, ns: not significant p > 0.05 (n = 6)

Back to article page

Thrombosis Journal

ISSN: 1477-9560

Contact us