Table 1 The characteristics of included studies in this meta-analysis
From: GST null polymorphisms may affect the risk of coronary artery disease: evidence from a meta-analysis
First author, year | Country | Ethnicity | Type of disease | Sample size Case/Control | Null genotype [n(%)] | NOS score | |
|---|---|---|---|---|---|---|---|
Cases Controls | |||||||
GSTM1 null | |||||||
Abu-Amero 2006 | Saudi Arabia | Mixed | Coronary artery disease (CAD) | 1054/762 | 655 (62.1%) | 117 (15.3%) | 7 |
Bazo 2011 | Brazil | Mixed | Coronary artery disease (CAD) | 297/96 | 160 (53.8%) | 40 (41.7%) | 7 |
Bhat 2016 | India | Mixed | Coronary artery disease (CAD) | 200/200 | 62 (31.0%) | 36 (18.0%) | 8 |
Bhatti 2018 | India | Mixed | Coronary artery disease (CAD) | 562/564 | 217 (38.6%) | 127 (22.5%) | 7 |
Cora 2013 | Turkey | Caucasian | Myocardial infarction (MI) | 324/296 | 182 (56.1%) | 143 (48.3%) | 8 |
Cornelis 2007 | Canada | Caucasian | Myocardial infarction (MI) | 2042/2042 | 980 (48.0%) | 1041 (51.0%) | 7 |
Evans 1996 | Saudi Arabia | Mixed | Coronary artery disease (CAD) | 90/884 | 57 (63.3%) | 484 (54.8%) | 7 |
Girisha 2004 | India | Mixed | Coronary artery disease (CAD) | 197/198 | 46 (23.4%) | 41 (20.7%) | 7 |
Hayek 2006 | Israel | Mixed | Coronary artery disease (CAD) | 193/2399 | 88 (45.6%) | 1142 (47.6%) | 8 |
Kadıoğlu 2016 | Turkey | Caucasian | Coronary artery disease (CAD) | 29/30 | 17 (58.6%) | 14 (46.7%) | 7 |
Kariž 2012 | Slovenia | Caucasian | Myocardial infarction (MI) | 206/257 | 142 (69.0%) | 166 (64.6%) | 7 |
Kim 2008 | Korea | East Asian | Coronary artery disease (CAD) | 356/336 | 198 (55.6%) | 191 (56.8%) | 7 |
Li 2000 | USA | Mixed | Coronary artery disease (CAD) | 400/790 | 178 (44.5%) | 354 (44.8%) | 7 |
Macie 2009 | Brazil | Mixed | Coronary artery disease (CAD) | 869/1573 | 557 (64.1%) | 789 (50.2%) | 7 |
Manfredi 2007 | Italy | Caucasian | Coronary artery disease (CAD) | 169/53 | 99 (58.6%) | 24 (45.3%) | 7 |
Manfredi 2009 | Italy | Caucasian | Coronary artery disease (CAD) | 184/47 | 108 (58.7%) | 18 (38.3%) | 7 |
Martin 2009 | USA | Mixed | Coronary artery disease (CAD) | 67/63 | 41 (61.2%) | 19 (30.2%) | 7 |
Masetti 2003 | Italy | Caucasian | Coronary artery disease (CAD) | 308/122 | 163 (52.9%) | 66 (54.1%) | 8 |
Mir 2016 | India | Mixed | Coronary artery disease (CAD) | 100/100 | 42 (42.0%) | 26 (26.0%) | 8 |
Nomani 2011 | Iran | Mixed | Coronary artery disease (CAD) | 209/108 | 100 (47.8%) | 57 (52.8%) | 8 |
Norskov 2011 | Denmark | Caucasian | Coronary artery disease (CAD) | 4930/21684 | 2052 (41.6%) | 11,362 (52.4%) | 7 |
Olshan 2003 | USA | Mixed | Coronary artery disease (CAD) | 526/868 | 252 (47.9%) | 352 (40.6%) | 8 |
Pašalić 2017 | Croatia | Caucasian | Coronary artery disease (CAD) | 71/174 | 29 (40.8%) | 69 (39.7%) | 7 |
Phulukdaree 2012 | India | Mixed | Coronary artery disease (CAD) | 102/100 | 37 (36.3%) | 18 (18.0%) | 7 |
Pourkeramati 2020 | Iran | Mixed | Coronary artery disease (CAD) | 244/281 | 128 (52.5%) | 138 (49.1%) | 8 |
Ramprasath 2011 | India | Mixed | Coronary artery disease (CAD) | 290/270 | 128 (44.1%) | 56 (20.7%) | 7 |
Salama 2002 | USA | Mixed | Coronary artery disease (CAD) | 130/90 | 45 (34.6%) | 33 (36.7%) | 7 |
Singh 2011 | India | Mixed | Myocardial infarction (MI) | 230/300 | 56 (24.3%) | 65 (21.7%) | 8 |
Tamer 2004 | Turkey | Caucasian | Coronary artery disease (CAD) | 148/247 | 67 (45.3%) | 103 (41.7%) | 7 |
Tang 2009 | China | East Asian | Coronary artery disease (CAD) | 277/277 | 89 (32,.1%) | 59 (21.3%) | 7 |
Taspinar 2012 | Turkey | Caucasian | Coronary artery disease (CAD) | 122/142 | 51 (41.8%) | 66 (46.5%) | 7 |
Wang 2002 | Australia | Caucasian | Coronary artery disease (CAD) | 612/256 | 343 (56.0%) | 153 (59.8%) | 7 |
Wang 2008 | China | East Asian | Coronary artery disease (CAD) | 277/277 | 89 (32.1%) | 59 (21.3%) | 8 |
Wilson 2000 | UK | Caucasian | Myocardial infarction (MI) | 356/187 | 191 (53.7%) | 107 (57.2%) | 8 |
Wilson 2003 | UK | Mixed | Coronary artery disease (CAD) | 170/203 | 70 (41.2%) | 107 (52.7%) | 7 |
Yeh 2013 | Taiwan | East Asian | Coronary artery disease (CAD) | 458/209 | 253 (55.2%) | 121 (57.9%) | 8 |
Zhang 2011 | China | East Asian | Coronary artery disease (CAD) | 255/145 | 120 (47.1%) | 46 (31.7%) | 7 |
GSTP1 null | |||||||
Bhat 2016 | India | Mixed | Coronary artery disease (CAD) | 200/200 | 132 (66.0%) | 104 (52.0%) | 8 |
Bhatti 2018 | India | Mixed | Coronary artery disease (CAD) | 560/545 | 366 (65.4%) | 307 (56.3%) | 7 |
Cornelis 2007 | Canada | Caucasian | Myocardial infarction (MI) | 2042/2042 | 817 (40.0%) | 817 (40.0%) | 7 |
Kariž 2012 | Slovenia | Caucasian | Myocardial infarction (MI) | 206/257 | 135 (65.5%) | 140 (54.5%) | 7 |
Kovacs 2014 | Hungary | Caucasian | Myocardial infarction (MI) | 54/78 | 27 (50.0%) | 26 (33.3%) | 7 |
Nomani 2011 | Iran | Mixed | Coronary artery disease (CAD) | 209/108 | 118 (56.4%) | 60 (55.5%) | 8 |
Phulukdaree 2012 | India | Mixed | Coronary artery disease (CAD) | 102/100 | 36 (35.3%) | 52 (52.0%) | 7 |
Pourkeramati 2020 | Iran | Mixed | Coronary artery disease (CAD) | 244/281 | 64 (26.2%) | 56 (19.9%) | 8 |
Ramprasath 2011 | India | Mixed | Coronary artery disease (CAD) | 290/270 | 196 (67.6%) | 152 (56.3%) | 7 |
Singh 2011 | India | Mixed | Myocardial infarction (MI) | 230/300 | 90 (39.1%) | 117 (39.0%) | 8 |
Yeh 2013 | Taiwan | East Asian | Coronary artery disease (CAD) | 458/209 | 125 (27.3%) | 59 (28.2%) | 8 |
GSTT1 null | |||||||
Abu-Amero 2006 | Saudi Arabia | Mixed | Coronary artery disease (CAD) | 1054/762 | 463 (43.9%) | 66 (8.7%) | 7 |
Bazo 2011 | Brazil | Mixed | Coronary artery disease (CAD) | 297/100 | 69 (23.2%) | 19 (19.0%) | 7 |
Bhat 2016 | India | Mixed | Coronary artery disease (CAD) | 200/200 | 12 (6.0%) | 25 (12.5%) | 8 |
Bhatti 2018 | India | Mixed | Coronary artery disease (CAD) | 562/564 | 86 (15.3%) | 129 (22.9%) | 7 |
Cora 2013 | Turkey | Caucasian | Myocardial infarction (MI) | 324/296 | 106 (32.7%) | 63 (21.3%) | 8 |
Cornelis 2007 | Canada | Caucasian | Myocardial infarction (MI) | 2042/2042 | 388 (19.0%) | 408 (20.0%) | 7 |
Decharatchakul 2020 | Thailand | East Asian | Coronary artery disease (CAD) | 279/735 | 115 (41.9%) | 242 (32.9%) | 8 |
García 2018 | Mexico | Mixed | Coronary artery disease (CAD) | 79/101 | 15 (19.0%) | 8 (7.9%) | 7 |
Girisha 2004 | India | Mixed | Coronary artery disease (CAD) | 197/198 | 15 (7.6%) | 36 (18.2%) | 7 |
Hayek 2006 | Israel | Mixed | Coronary artery disease (CAD) | 193/2399 | 30 (15.5%) | 392 (16.3%) | 8 |
Kadıoğlu 2016 | Turkey | Caucasian | Coronary artery disease (CAD) | 29/30 | 6 (20.7%) | 5 (16.7%) | 7 |
Kariž 2012 | Slovenia | Caucasian | Myocardial infarction (MI) | 206/257 | 77 (37.4%) | 108 (42.0%) | 7 |
Kim 2008 | Korea | East Asian | Coronary artery disease (CAD) | 356/336 | 196 (55.0%) | 187 (55.7%) | 7 |
Li 2000 | USA | Mixed | Coronary artery disease (CAD) | 400/890 | 74 (18.5%) | 166 (18.7%) | 7 |
Lakshmi 2012 | India | Mixed | Coronary artery disease (CAD) | 352/282 | 81 (23.0%) | 39 (13.8%) | 7 |
Levinsson 2014 | Sweden | Caucasian | Coronary artery disease (CAD) | 112/1221 | 11 (9.8%) | 168 (13.8) | 7 |
Macie 2009 | Brazil | Mixed | Coronary artery disease (CAD) | 869/1573 | 209 (24.1%) | 337 (21.4%) | 7 |
Manfredi 2007 | Italy | Caucasian | Coronary artery disease (CAD) | 169/53 | 95 (56.2%) | 13 (24.5%) | 7 |
Manfredi 2009 | Italy | Caucasian | Coronary artery disease (CAD) | 184/47 | 84 (45.7%) | 13 (27.7%) | 7 |
Martin 2009 | USA | Mixed | Coronary artery disease (CAD) | 67/63 | 12 (17.9%) | 12 (19.7%) | 7 |
Masetti 2003 | Italy | Caucasian | Coronary artery disease (CAD) | 308/122 | 117 (38.0%) | 40 (32.8%) | 8 |
Mir 2016 | India | Mixed | Coronary artery disease (CAD) | 100/100 | 23 (23.0%) | 16 (16.0%) | 8 |
Nomani 2011 | Iran | Mixed | Coronary artery disease (CAD) | 209/108 | 16 (7.7%) | 17 (15.7%) | 8 |
Norskov 2011 | Denmark | Caucasian | Coronary artery disease (CAD) | 4930/21684 | 740 (15.0%) | 3161 (14.6%) | 7 |
Olshan 2003 | USA | Mixed | Coronary artery disease (CAD) | 526/868 | 75 (14.3%) | 165 (19.0%) | 8 |
Palmer 2003 | UK | Caucasian | Coronary artery disease (CAD) | 51/57 | 40 (78.4%) | 35 (61.4%) | 7 |
Pašalić 2017 | Croatia | Caucasian | Coronary artery disease (CAD) | 68/177 | 17 (25.0%) | 54 (30.5%) | 7 |
Pourkeramati 2020 | Iran | Mixed | Coronary artery disease (CAD) | 244/281 | 129 (52.9%) | 143 (50.8%) | 8 |
Ramprasath 2011 | India | Mixed | Coronary artery disease (CAD) | 290/492 | 136 (46.9%) | 118 (24.0%) | 7 |
Salama 2002 | USA | Mixed | Coronary artery disease (CAD) | 130/90 | 32 (26.7%) | 14 (15.6%) | 7 |
Singh 2011 | India | Mixed | Myocardial infarction (MI) | 230/300 | 23 (10.0%) | 61 (20.3%) | 8 |
Tamer 2004 | Turkey | Caucasian | Coronary artery disease (CAD) | 148/247 | 48 (32.4%) | 70 (28.3%) | 7 |
Tang 2009 | China | East Asian | Coronary artery disease (CAD) | 277/277 | 77 (27.8%) | 53 (19.1%) | 7 |
Taspinar 2012 | Turkey | Caucasian | Coronary artery disease (CAD) | 122/142 | 28 (23.0%) | 25 (17.6%) | 7 |
Wang 2008 | China | East Asian | Coronary artery disease (CAD) | 277/277 | 77 (27.8%) | 53 (19.1%) | 8 |
Wilson 2000 | UK | Caucasian | Myocardial infarction (MI) | 356/187 | 90 (25.3%) | 36 (19.3%) | 8 |
Wilson 2003 | UK | Mixed | Coronary artery disease (CAD) | 170/203 | 34 (20.0%) | 44 (21.7%) | 7 |
Yeh 2013 | Taiwan | East Asian | Coronary artery disease (CAD) | 458/209 | 276 (60.3%) | 110 (52.6%) | 8 |
Zhang 2011 | China | East Asian | Coronary artery disease (CAD) | 255/145 | 141 (55.3%) | 60 (41.4%) | 7 |