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Table 2 Integrated analyses for GST null polymorphisms and CAD

From: GST null polymorphisms may affect the risk of coronary artery disease: evidence from a meta-analysis

Polymorphisms Population Sample size
(Cases/controls)
Null genotype vs. Present genotype
P value OR (95%CI) I2 statistic
GSTM1 null CAD 17,054/36630 0.003 1.37 (1.11-1.70) 95%
Caucasian 9501/25537 0.72 1.04 (0.85-1.26) 84%
East Asian 1623/1244 0.07 1.35 (0.97-1.88) 76%
Mixed population 5930/9849 0.004 1.61 (1.16-2.22) 94%
GSTP1 null CAD 4595/4390 0.03 1.23 (1.02-1.48) 70%
Caucasian 2302/2377 0.17 1.35 (0.88-2.07) 76%
Mixed population 1835/1804 0.11 1.23 (0.96-1.59) 68%
GSTT1 null CAD 17,120/38115 0.02 1.23 (1.03-1.46) 89%
Caucasian 9049/26562 0.02 1.23 (1.03-1.47) 67%
East Asian 1902/1979 < 0.0001 1.38 (1.20-1.59) 36%
Mixed population 6169/9574 0.61 1.11 (0.76-1.62) 94%
  1. Abbreviations: OR Odds ratio, CI Confidence interval, NA Not available, CAD Coronary artery disease
  2. The values in bold represent there is statistically significant differences between cases and controls