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Table 2 Risk factors predisposing to VTE in puerperium of women age ≥ 35

From: The predictive value of D-dimer test for venous thromboembolism during puerperium in women age 35 or older: a prospective cohort study

Risk factors VTE(%)
(n = 30)
Non-VTE(%)
(n = 12,421)
χ2 value P value
Previous obstetric history
 0 11 (36.67) 2938 (23.65) 2.804 .094
 ≥ 1 19 (63.33) 9483 (76.35)   
Parity
 1 30 (100.00) 12,048 (97.00)   1.000a
 ≥ 2 0 (0.00) 373 (3.00)   
Fetal position of singleton cases
 Head 28 (93.33) 11,406 (94.67)   .385a
 Breech 1 (3.33) 506 (4.20)   
 Transverse 1 (3.33) 136 (1.13)   
Mode of delivery
 Vaginal delivery 2 (6.67) 4786 (38.53) 25.792 <.001
 Emergency cesarean section 16 (53.33) 2399 (19.31)   
 Elective caesarean section 12 (40.00) 5236 (42.15)   
In vitro fertilization (IVF) 0 (0.00) 678 (5.46) 0.834 .361
Scared uterus 20 (66.67) 5612 (45.18) 5.58 .018
Relative cephalopelvic disproportion 0 (0.00) 164 (1.32)   1.000a
Placenta previa 3 (10.00) 612 (4.93) 0.738 .390
Adherent placenta 4 (13.33) 610 (4.91) 2.910 .088
Fetal growth restriction 0 (0.00) 182 (1.47)   1.000a
Premature birth 5 (16.67) 1557 (12.54) 0.165 .684
Macrosomia (birthweight≥4000 g) 1 (3.33) 789 (6.35) 0.092 .762
Premature rupture of membranes 7 (23.33) 2184 (17.58) 0.682 .409
Fetal distress 5 (16.67) 1566 (12.61) 0.155 .694
Intrauterine infection 1 (3.33) 139 (1.12)   .288a
Postpartum hemorrhage 3 (10.00) 458 (3.69) 1.809 .179
Anemia 9 (30.00) 2654 (21.37) 1.327 .249
Intrahepatic cholestasis of pregnancy 3 (10.00) 398 (3.20)   .071a
Gestational diabetes mellitus 3 (10.00) 2951 (23.76) 3.130 .077
Hypertensive disorders of pregnancy 3 (10.00) 924 (7.44) 0.034 .853
Cardiac insufficiency 0 (0.00) 20 (0.16)   1.000a
Uterine rupture 0 (0.00) 84 (0.68)   1.000a
D-dimer≥5.545 mg /L 21 (70.00) 3057 (24.61) 33.130 <.001
D-dimer≥6.475 mg /L 16 (53.33) 2480 (19.97) 20.789 <.001
D-dimer≥9.88 mg /L 11 (36.67) 1242 (10.00) 20.661 <.001
  1. a evaluated by Fisher’s exact test