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Table 1 Selected characteristics of the study participants

From: The association of alcohol with circulating total fibrinogen and plasma clot density is mediated by fibrinogen and FXIII genotypes

Median (interquartile range) or (n: n)
  Whole group Abstainers Drinkers Differences between abstainers and drinkers (p value)
Gender (Men: Women)# 747: 1263 259: 818 465: 407 < 0.001
Age (yr) 48.0 (41.0–56.0) 48.5 (41.5–57.5) 48.0 (42.1–55.4) 0.20
Blood pressure (mmHg)
 Diastolic 87.0 (78.0–97.0) 85.0 (76.0–95.0) 89.0 (79.0–99.0) < 0.0001
 Systolic 130 (116–147) 127 (114–144) 133 (120–150) < 0.0001
Tobacco use (%)     
 Never (1) 52.7  4.3 3.5 < 0.0001
 Former (2) 4.14 38.3 69.6
 Current (3) 42.7 57.4 26.9
PA index 7.33 (5.79–8.67) 7.70 (6.00–8.80) 6.80 (5.50–8.40) < 0.0001
BMI (kg/m2) 22.9 (19.3–28.6) 25.1 (20.8–31.0) 20.9 (18.4–24.9) < 0.001
Waist circumference (cm) 77.5 (70.2–87.7) 81.0 (71.6–90.3) 74.4 (69.3–83.2) < 0.0001
Biochemical markers HIV status (Unaffected n: Affected n)# 1668: 326 917: 157 707: 156 0.04
TC (mmol/L) 4.82 (4.01–5.87) 4.93 (4.11–6.05) 4.74 (3.95–5.67) 0.001
LDL-C (mmol/L) 2.79 (2.08–3.65) 3.02 (2.25–3.88) 2.56 (1.87–3.25) < 0.0001
HDL-C (mmol/L) 1.42 (1.06–1.87) 1.32 (1.02–1.67) 1.60 (1.14–2.09) < 0.0001
Triglycerides (mmol/L) 1.08 (0.82–1.55) 1.12 (0.82–1.56) 1.30 (0.36–7.88) 0.08
HbA1c (%) 5.50 (5.30–5.80) 5.60 (5.30–5.90) 5.50 (5.10–5.80) < 0.0001
CRP (mg/L) 3.29 (0.96–9.34) 3.40 (0.89–9.44) 3.04 (1.04–9.13) 0.68
Total fibrinogen (g/l) 2.90 (2.30–5.00) 3.10 (2.40–5.50) 2.70 (2.10–4.30) < 0.0001
Fibrinogen γ’ (%) 10.2 (7.14–14.6) 10.3 (7.12–14.7) 10.1 (7.34–14.6) 0.81
Lag time (min) 6.52 (5.10–7.78) 6.50 (5.13–7.77) 6.58 (5.10–7.78) 0.96
Slope (×10−03 au/s) 8.90 (6.49–11.9) 9.23 (6.72–12.3) 8.52 (6.15–11.6) < 0.001
Maximum absorbance (nm) 0.42 (0.33–0.52) 0.43 (0.35–0.53) 0.40 (0.31–0.49) < 0.001
CLT (min) 57.2.(50.9–63.8) 59.2 (53.8–66.0) 52.3 (47.5–60.5) < 0.001
GGT (U/l) 46.0 (29.7–88.0) 36.4 (26.3–55.0) 73.0 (40.1–157) < 0.001
%CDT 2.67 (1.97–3.59) 2.35 (1.80–3.08) 3.07 (2.30–4.32) < 0.001
GGT-CDT 4.37 (3.76–5.12) 3.98 (3.54–4.52) 4.99 (4.29–5.72) < 0.001
ALT (IU/L) 17.1 (12.0–25.1) 16.0 (11.6–21.8) 19.5 (13.0–29.1) < 0.001
AST (IU/L) 26.0 (19.2–39.0) 23.2 (18.0–31.0) 31.7 (22.0–52.1) < 0.001
Dietary intake Alcohol intake of consumers (g/day); abstainers: drinkers (n:n)# 15.4 (6.43–34.7);
824: 659
15.4 (6.43–34.7)
Energy (kJ) 7175 (5268–10,001) 6508 (4834–8763) 8077 (5953–11,792) < 0.001
Protein (%TE) 11.6 (10.4–12.9) 11.6 (10.3–12.8) 11.6 (10.5–13.0) 0.13
Carbohydrate (%TE) 60.3 (54.2–67.5) 63.1 (56.2–69.6) 57.5 (52.4–63.3) < 0.001
Total fat (%TE) 22.5 (17.4–27.7) 22.7 (18.1–28.2) 22.4 (16.6–27.1) < 0.001
  1. ALT Alanine transaminase, AST Aspartate aminotransferase, BMI Body mass index, CLT Clot lysis time, CRP High sensitivity C-reactive protein, %CDT Percentage carbohydrate deficient transferrin, GGT Gamma-glutamyltransferase, GGT-CDT 0.8 x ln(GGT) + 1.3 x ln(%CDT), HbA1c Glycosylated haemoglobin A1c, HDL-C High-density lipoprotein cholesterol, HIV Human immunodeficiency virus, LDL-C Low-density lipoprotein cholesterol; n, number of patients, PA Physical activity, PAI-1act Plasminogen activator inhibitor type-1 activity, TC Total cholesterol, TE Total energy
  2. #Total sample is 2010, but numbers are slightly different for several variables including alcohol intake due to missing data