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Table 1 The evaluation of risk factors for thromboembolism during pregnancy and puerperium

From: Maternal mortality following thromboembolism; incidences and prophylaxis strategies

Risk Factors

Score

A) Risk factors related to general conditions

Body mass index (BMI) equal to or greater than 40 (before or during early pregnancy)

2

Age older than 35 years

1

BMI between 35 and 40 (before or early pregnancy / weight greater than 80 kg)

1

Parity ≥ 3 regardless of the current pregnancy

1

Smoking

1

Gross varicose veins (symptomatic or above the knee or with phlebitis, edema, skin changes)

1

B) Risk factors related to medical conditions

History of previous VTE (except for the reason of major surgery)

4

Acquired thrombophilia (antiphospholipid antibody syndrome): at least one laboratory test and at least a clinical criterion

4

History of previous VTE due to major surgery

3

Any medical conditions: cancer, cardiac disease, active lupus, inflammatory poly-arthropathy or inflammatory bowel disease, nephrotic syndrome, type 1 diabetes mellitus with nephropathy, tuberculosis, current intravenous drug addiction

3

High risk inherited thrombophilia (deficiency of anti-thrombin, protein S or C deficiency, homozygote low risk thrombophilia or more than one heterozygote low risk thrombophilia)

3

Low risk inherited thrombophilia (heterozygote factor 5 Leiden, G20210A prothrombin gene mutation)

1

Family history of VTE in first degree relatives (spontaneous or estrogen dependent)

1

Anti-phospholipid antibodies (only laboratory criteria, without a clinical criteria)

1

C) Obstetrical Risk Factors

Cesarean section in labor

2

Current preeclampsia

1

Pregnancy with fertility IVF / ART methods (only considered during pregnancy)

1

Multiple pregnancy

1

Non-emergency cesarean (elective)

1

Instrumental delivery

1

Prolonged labor (more than 24 h)

1

Postpartum hemorrhage (greater than 1 l / blood transfusion)

1

Preterm labor (less than 37 weeks) in the current pregnancy

1

Intrauterine fetal demise (IUFD) in the current pregnancy

1

D) Transient Risk Factors

Ovarian hyper stimulation syndrome (only in the first trimester)

4

Surgery during pregnancy or postpartum (curettage, tubal closure, appendectomy..., except for perineal immediate repair)

3

Severe vomiting of pregnancy (hyperemesis)

3

Systemic infections (antibiotics or admission needed) foe example: pneumonia, pyelonephritis, postpartum wound infection

1

Hospitalization or immobilization (≥3 days rest in bed), dehydration

1