Infectious disease | Hematological disease | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Fibrinogen, g/L | ≥1.5 | < 1.5 | p-value | ≥1.5 | < 1.5 | p-value | ||||
Age, years | 1865 | 71 (60–79) | 215 | 70 (53–79) | 0.1094 | 809 | 61 (43–70) | 311 | 63 (41–73) | 0.0578 |
Male | 1868 | 1096 (58.7) | 215 | 109 (50.7) | 0.0249 | 809 | 506 (62.5) | 312 | 165 (52.9) | 0.0045 |
Body weight, kg | 1861 | 50 (40–60) | 215 | 53 (45–62) | 0.0005 | 808. | 55 (48.4–64) | 312 | 55 (48.2–63.8) | 0.7995 |
SOFA score | 1164 | 10 (7–13) | 118 | 11 (8–15) | 0.0144 | – | – | – | – | – |
JMHW DIC score | 1081 | 6 (5–7) | 104 | 9 (7–10) | < 0.0001 | 551 | 4 (3–5) | 226 | 6 (5–7) | < 0.0001 |
ISTH DIC score | 580 | 4 (4–5) | 54 | 5 (4–7) | 0.0002 | 209 | 5 (4–6) | 81 | 6 (5–7) | < 0.0001 |
JAAM DIC score | 1198 | 5 (4–7) | 119 | 6 (5–8) | 0.0005 | – | – | – | – | – |
Pre-administration | 1868 | 215 | 809 | 312 | ||||||
AT concentrate | 364 (19.5) | 27 (12.6) | 0.0138 | 62 (7.7) | 13 (4.2) | 0.0357 | ||||
Gabexate mesylate | 343 (18.4) | 42 (19.5) | 0.6748 | 61 (7.5) | 29 (9.3) | 0.3326 | ||||
Nafamostat mesylate | 175 (9.4) | 12 (5.6) | 0.0658 | 29 (3.4) | 12 (3.8) | 0.8344 | ||||
Unfractionated heparin | 91 (4.9) | 6 (2.8) | 0.1703 | 29 (2.4) | 7 (2.2) | 0.2537 | ||||
LMWH | 34 (1.8) | 5 (2.3) | 0.6046 | 65 (8.0) | 10 (3.2) | 0.0037 | ||||
Danaparoid sodium | 66 (3.5) | 8 (3.7) | 0.8880 | 31 (3.8) | 20 (6.4) | 0.0634 | ||||
Comorbidities | 1868 | 215 | 809 | 312 | ||||||
Bleeding symptoms | 234 (12.5) | 54 (25.1) | < 0.0001 | 225 (27.8) | 144 (46.2) | < 0.0001 | ||||
Organ symptoms | 861 (46.1) | 116 (54.0) | 0.0292 | 221 (27.3) | 71 (22.8) | 0.1189 |