Table 2 Outcomes of infectious disease or hematological disease patients in with or without hypofibrinogenemia
Infectious diseases | Hematological diseases | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Fibrinogen, g/L | ≥1.5 | < 1.5 | p-value | ≥1.5 | < 1.5 | p-value | ||||
28-day survival | 1846 | 1321 (71.6) | 212 | 106 (50.0) | < 0.0001 | 807 | 587 (72.7) | 312 | 220 (70.5) | 0.4566 |
JMHW DIC resolution | 683 | 427 (62.5) | 98 | 47 (48.0) | 0.0058 | 476 | 275 (57.8) | 231 | 113 (48.9) | 0.0265 |
ISTH DIC resolution | 651 | 449 (69.0) | 119 | 57 (47.9) | < 0.0001 | 385 | 240 (62.3) | 202 | 116 (57.4) | 0.2472 |
JAAM DIC resolution | 1266 | 513 (40.5) | 156 | 30 (19.2) | < 0.000 | – | – | – | – | |
Clinical course of bleeding symptoms | ||||||||||
Disappeared+Improved | 216 | 99 (45.8) | 48 | 24 (50.0) | 0.6007 | 217 | 110 (50.7) | 142 | 86 (60.6) | 0.0662 |
Unchanged+Exacerbated | 216 | 117 (54.2) | 48 | 24 (50.0) | 217 | 107 (49.3) | 142 | 56 (39.4) | ||