| |
Controls (n = 10)
|
Rivaroxaban (n = 10)
|
Apixaban (n = 10)
|
Edoxaban (n = 10)
|
Dabigatran (n = 10)
|
Phenprocoumon (n = 10)
|
LMWH (n = 10)
|
UFH (n = 10)
|
|---|
|
Female/male gender, n (%)
|
6/4 (60/40)
|
5/5 (50/50)
|
8/2 (80/20)
|
9/1 (90/10)
|
8/2 (80/20)
|
6/4 (60/40)
|
6/4 (60/40)
|
3/7 (30/70)
|
|
Age (years)
|
60 (58–64)
|
71 (54–81)
|
82 (79–87)
|
77 (73–83)
|
72 (58–79)
|
82 (45–86)
|
70 (42–79)
|
74 (63–82)
|
|
BMI (kg/m2)
|
27.1 (25.6–30.7)
|
23.7 (22.0–31.7)
|
23.9 (23.2–26.0)
|
27.0 (24.0–29.2)
|
26.3 (23.6–29.5)
|
26.6 (24.6–30.2)
|
24.3 (20.3–28.1)
|
26.6 (22.0–27.9)
|
|
ASA status, n (%)
|
|
1
|
2 (20)
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
|
2
|
8 (80)
|
2 (20)
|
0
|
0
|
3 (30)
|
0
|
1 (10)
|
0
|
|
3
|
0
|
8 (80)
|
10 (100)
|
10 (100)
|
7 (70)
|
10 (100)
|
9 (90)
|
9 (90)
|
|
4
|
0
|
0
|
0
|
0
|
0
|
0
|
0
|
1 (10)
|
|
Diabetes, n (%)
|
|
Yes
|
0
|
2 (20)
|
2 (20)
|
2 (20)
|
2 (20)
|
4 (40)
|
1 (10)
|
3 (30)
|
|
No
|
10 (100)
|
8 (80)
|
8 (80)
|
8 (80)
|
8 (80)
|
6 (60)
|
9 (90)
|
6 (70)
|
|
Creatinine (mg/dL)
|
0.9 (0.78–0.95)
|
1.0 (0.89–1.49)
|
1.2 (1.2–1.4)
|
1.2 1.1–1.4)
|
1.1 (0.9–1.3)
|
1.5 (1.1–2.6)
|
1.1 (0.88–1.4)
|
1.0 (0.6–2.5)
|
|
GFR (ml/min)
|
96 (93–106)
|
79 (65–99)
|
56 (48–82)
|
71 (52–81)
|
74 (64–104)
|
61 (35–84)
|
92 (70–112)
|
73 (23–86)
|
|
Platelets (109/L)
|
262 (210–289)
|
214 (141–265)
|
247 (159–294)
|
220 (180–271)
|
229 (184–293)
|
239 (170–266)
|
282 (211–330)
|
227 (156–350)
|
|
Hb (mg/dL)
|
14.3 (13.7–15.2)
|
12.5 (10.0–14.6)
|
11.8 (9.9–13.6)
|
13.1 (11.9–14.1)
|
13.6 (11.4–15.1)
|
12.2 (10.7–15.3)
|
11.0 (9.4–12.6)
|
8.3 (7.4–9.1)
|
|
Hematocrit
|
0.41 (0.39–0.43)
|
0.38 (0.31–0.43)
|
0.36 (0.3–0.41)
|
0.38 (0.37–0.41)
|
0.40 (0.34–0.44)
|
0.36 (0.32–0.45)
|
0.31 (0.28–0.35)
|
0.26 (0.22–0.28)
|
|
Fibrinogen (mg/dL)
|
367 (325–411)
|
413 (359–447)
|
530 (366–594)
|
481 (310–570)
|
365 (298–425)
|
420 (390–500)
|
429 (341–597)
|
414 (319–509)
|
- ASA American society of anesthesiologist status; BMI body mass index; GFR glomerular filtration rate; Hb hemoglobin; LMWH low molecular weight heparin; UFH unfractionated heparin
