Table 3 (a) Odds ratio of clinical and laboratory factors for thrombotic (arterial and venous) and major bleeding events. (b) Association of thrombotic and major bleeding events to mortality

 Age

1.034

.990

1.080

.13

1.026

.980

1.075

.27

 Gender, male

1.966

.603

6.414

.26

1.381

.410

4.650

.60

 Ethnicity, Chinese

.900

.333

2.430

.84

.754

.257

2.207

.61

 Diabetes

.505

.168

1.514

.22

.740

.237

2.310

.60

 Hypertension

1.140

.424

3.065

.80

.704

.243

2.040

.52

 Hyperlipidemia

1.800

.670

4.835

.24

1.091

.377

3.155

.87

 Renal impairment

1.118

.284

4.399

.87

2.455

.672

8.962

.17

 Pre-existing cardiovascular disease^a

1.667

.562

4.945

.36

.780

.203

2.999

.72

 APAHCE score

.979

.904

1.061

.61

.997

.918

1.082

.94

 SOFA score

1.043

.890

1.224

.60

1.161

.993

1.358

.06

 Mechanical ventilation

3.000

.644

13.973

.16

5.000

.626

39.963

.13

 Dialysis support

1.718

.606

4.867

.31

4.940

1.629

14.978

.005

 Use of thromboprophylaxis

.492

.184

1.313

.16

.376

.128

1.108

.08

 PT

1.133

.965

1.329

.13

1.060

.906

1.241

.47

 aPTT

.999

.967

1.032

.97

1.003

.967

1.041

.88

 D-dimer

1.030

.929

1.143

.57

.783

.454

1.352

.38

 Fibrinogen

.956

.751

1.217

.78

.658

.453

.957

.03

 White blood count

1.037

.962

1.117

.35

.994

.906

1.089

.89

 Absolute lymphocyte count

1.246

.698

2.226

.46

.573

.217

1.511

.26

 Absolute neutrophils count

1.030

.945

1.123

.50

1.001

.905

1.107

.99

 Platelet count

.999

.996

1.002

.60

.998

.995

1.002

.35

 C-reactive protein

.995

.989

1.001

.09

1.001

.995

1.006

.75

 Procalcitonin

.996

.969

1.023

.76

.937

.776

1.132

.50

 Creatinine

1.000

.996

1.004

.86

.999

.995

1.004

.78

b) Factors

Thrombotic events

4.150

1.004

17.161

.05

 Arterial events

4.450

.961

20.599

.06

 Venous events

1.937

.207

18.141

.56

Major bleeding events

3.308

.735

14.878

.12