Fig. 2
a The clinical course of the patient. Lupus anticoagulant remained high, even with hydrocortisone administration. At diagnosis of SLE, high levels of antinuclear antibody are shown. After intravenous pulse treatments with methylprednisolone (30 mg/kg/day) and cyclophosphamide (500 mg/m2), a decrease in lupus anticoagulant and antinuclear antibody levels are shown. Abbreviations: IVCY, intravenous cyclophosphamide; mPSL, methylprednisolone; MMF, mycofenolate mofetil; aPTT, activated partial thromboplastin time. b and c Immunofluorescence micrographs of renal biopsy specimens. b, granular IgG deposits in the glomerular capillary walls, in a diffuse and global distribution. c, granular deposits of C1q on the glomerular basement membrane