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Table 3 Logistic regression analysis of D-dimer-related factors

From: Peripherally inserted central venous catheter in upper extremities leads to an increase in D-dimer and deep vein thrombosis in lower extremities

Factors D-dimer
(> 0.5 mg/L)
D-dimer
(≤ 0.5 mg/L)
Univariate Multivariate
n = 597 s = 763 OR (95 % CI) P OR (95 % CI) P
PICC 80 21 5.467 (3.338–8.956) 0.000 3.354 (1.733–6.346) 0.000
Age (year, mean ± standard deviation) 61.91 ± 15.50 60.17 ± 14.46 1.008 (1.001–1.015) 0.033 1.014 (1.006–1.022) 0.001
Male 339 486 0.749 (0.602–0.932) 0.010 0.852 (0.670–1.082) 0.189
Malignant tumor 85 38 3.167 (2.126–4.720) 0.000 0.785 (0.430–1.435) 0.432
Recent surgery 158 64 3.931 (2.872–5.381) 0.000 4.944 (3.015–8.107) 0.000
Cerebral hemorrhage 58 41 1.895 (1.251–2.870) 0.003 1.245 (0.772–2.009) 0.369
Ischemic stroke 192 330 0.622 (0.497–0.778) 0.000 0.691 (0.531–0.901) 0.006
Parkinson’s disease 19 64 0.359 (0.213–0.606) 0.000 0.461 (0.266-0.800) 0.006
Infection 121 85 2.028 (1.500–2.740) 0.000 3.078 (2.218–4.271) 0.000
BMI ≥ 25 42 57 0.937 (0.620–1.148) 0.759 0.641 (0.400-1.026) 0.064
Unconsciousness 126 127 1.340 (1.019–1.762) 0.036 0.828 (0.579–1.184) 0.301
Critical illness 78 38 2.867 (1.915–4.294) 0.000 2.844 (1.754–4.613) 0.000
  1. Note: PICC refers to peripherally inserted central venous catheter; BMI refers to body mass index; malignant tumor refers to cases treated within the prior six months; recent surgery refers to neurosurgery (over two hours) performed within six months; critical illness refers to the circumstance where patients have a high risk of disease variation or death