Table 1 Severity Classification Criteria and Therapeutic Strategy for critical COVID-19
● Criteria for severe COVID-19 | ||
1) SpO2 < 92% at 10 L/min. Oxygen via a reservoir mask | ||
2) Shortness of breath with respiratory rate of > 30/min. | ||
3) Severe dyspnea due to COVID-19 pneumonia | ||
● Therapeutic strategy for critical COVID-19 [11] | ||
1) Mechanical ventilator | mode | pressure control |
(primary setting) | PEEP | 10–15 mmH2O |
Driving Pressure | 20–25 mmH2O | |
Respiratory Rate | 12–16/min. | |
2) Antiviral therapy | Remdesivir [12] | 10 days |
3) Systemic steroid therapy | Dexamethasone [13] | 10 days |
4) Anticoagulant therapy | UFH with therapeutic dose according to APTT (1.5–2 times as normal) | |
5) Protection for DVT | Intermittent air compression and elastic stocking | |
6) Antibiotics | for CAP or secondary bacterial or fungus infection | |
7) Rehabilitation | early intervention by NS, PT and OT | |
8) Nutrition | early intervention via tube feeding or TPN | |
9) Supportive therapy | sedation,catecholamine support etc. via central venous catheter | |