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Table 1 Severity Classification Criteria and Therapeutic Strategy for critical COVID-19

From: An evaluation of venous thromboembolism by whole-body enhanced CT scan for critical COVID-19 pneumonia with markedly rises of coagulopathy related factors: a case series study

Criteria for severe COVID-19
1) SpO2 < 92% at 10 L/min. Oxygen via a reservoir mask
2) Shortness of breath with respiratory rate of > 30/min.
3) Severe dyspnea due to COVID-19 pneumonia
Therapeutic strategy for critical COVID-19 [11]
1) Mechanical ventilator mode pressure control
(primary setting) PEEP 10–15 mmH2O
Driving Pressure 20–25 mmH2O
Respiratory Rate 12–16/min.
2) Antiviral therapy Remdesivir [12] 10 days
3) Systemic steroid therapy Dexamethasone [13] 10 days
4) Anticoagulant therapy UFH with therapeutic dose according to APTT (1.5–2 times as normal)
5) Protection for DVT Intermittent air compression and elastic stocking
6) Antibiotics for CAP or secondary bacterial or fungus infection  
7) Rehabilitation early intervention by NS, PT and OT  
8) Nutrition early intervention via tube feeding or TPN  
9) Supportive therapy sedation,catecholamine support etc. via central venous catheter
  1. PEEP Positive end-expiratory pressure, PS Pressure support, UFH Unfractionated heparin, APTT Activated partial thromboplastin time, CAP Community associated pneumonia, NS Nurse, PT Physical therapist, OT Occupational therapist, TPN Total parenteral nutrition