An evaluation of venous thromboembolism by whole-body enhanced CT scan for critical COVID-19 pneumonia with markedly rises of coagulopathy related factors: a case series study

Table 1 Severity Classification Criteria and Therapeutic Strategy for critical COVID-19

● Criteria for severe COVID-19
1) SpO₂ < 92% at 10 L/min. Oxygen via a reservoir mask
2) Shortness of breath with respiratory rate of > 30/min.
3) Severe dyspnea due to COVID-19 pneumonia
● Therapeutic strategy for critical COVID-19 [11]
1) Mechanical ventilator	mode	pressure control
(primary setting)	PEEP	10–15 mmH₂O
	Driving Pressure	20–25 mmH₂O
	Respiratory Rate	12–16/min.
2) Antiviral therapy	Remdesivir [12]	10 days
3) Systemic steroid therapy	Dexamethasone [13]	10 days
4) Anticoagulant therapy	UFH with therapeutic dose according to APTT (1.5–2 times as normal)
5) Protection for DVT	Intermittent air compression and elastic stocking
6) Antibiotics	for CAP or secondary bacterial or fungus infection
7) Rehabilitation	early intervention by NS, PT and OT
8) Nutrition	early intervention via tube feeding or TPN
9) Supportive therapy	sedation,catecholamine support etc. via central venous catheter

PEEP Positive end-expiratory pressure, PS Pressure support, UFH Unfractionated heparin, APTT Activated partial thromboplastin time, CAP Community associated pneumonia, NS Nurse, PT Physical therapist, OT Occupational therapist, TPN Total parenteral nutrition

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