Fig. 1
From: The role of Sphingomyelin synthase 2 (SMS2) in platelet activation and its clinical significance
Human, mouse and rat platelets express SMS2. a Western blot detection of SMS2 in platelets from WT mice, SMS2 –/– mice, SH-SY5Y cell line, rats and human subjects. b PCR detection of monocyte-specific marker CD14. c, d Platelet count and mean volume in the peripheral blood of WT (black) and SMS2 –/– (red) mice (n = 8, n.s. P > 0.05). e, f Morphology of WT and SMS2 –/– platelets observed by transmission electron microscope. The average number of alpha and dense particles were calculated and no significant difference was found between WT and SMS2 –/– platelets (n = 10, n.s. P > 0.05)