Platelet adhesion in type 2 diabetes: impact of plasma albumin and mean platelet volume

Thrombosis Journal

Table 2 Relationship between plasma albumin and platelet adhesion at different conditions by Pearson correlation coefficients (Pearson r, P < 0.05 bold). Albumin surface (Alb); adenosine diphosphate (ADP); Adrenaline (Adr); Ristocetin (Ri); Collagen surface (Coll); Fibrinogen surface (Fib)

Surface + concentration of soluble activator	Healthy controls (n = 60)		Type 2 diabetic patients (n = 60)
Surface + concentration of soluble activator	Pearson r	P value	Pearson r	P value
Alb	-0,048	0,416	-0,022	0,862
Alb + 0.1 µmol/L ADP	-0,06	0,461	0,012	0,923
Alb + 1.0 µmol/L ADP	-0,037	0,970	0,159	0,197
Alb + 10 µmol/L ADP	-0,145	0,837	0,286	*0,018*
Alb + 0.1 µmol/L Adr	-0,037	0,357	0,211	0,089
Alb + 1.0 µmol/L Adr	-0,066	0,187	0,240	0,052
Alb + 0,1 mg/mL Ri	-0,057	0,364	0,048	0,696
Alb + 1,0 mg/mL Ri	0,084	0,382	0,120	0,334
Coll	0,022	0,353	0,316	*0,009*
Coll + 0.1 µmol/L ADP	-0,055	0,316	0,300	*0,014*
Coll + 1.0 µmol/L ADP	-0,092	0,567	0,329	*0,006*
Coll + 10 µmol/L ADP	-0,124	0,919	0,324	*0,007*
Coll + 0.1 µmol/L Adr	-0,090	0,364	0,335	*0,005*
Coll + 1.0 µmol/L Adr	-0,083	0,409	0,314	*0,009*
Coll + 0,1 mg/mL Ri	-0,046	0,217	0,296	*0,020*
Coll + 1,0 mg/mL Ri	-0,240	0,206	0,199	0,106
Fib	-0,177	0,794	0,301	*0,013*
Fib + 0.1 µmol/L ADP	-0,203	0,537	0,317	*0,009*
Fib + 1.0 µmol/L ADP	-0,138	0,441	0,356	*0,003*
Fib + 10 µmol/L ADP	-0,070	0,872	0,358	*0,003*
Fib + 0.1 µmol/L Adr	-0,089	0,353	0,071	0,566
Fib + 1.0 µmol/L Adr	-0,090	0,377	0,390	*0,001*
Fib + 0,1 mg/mL Ri	-0,222	0,920	0,329	*0,009*
Fib + 1,0 mg/mL Ri	-0,191	0,532	0,221	0,072

ISSN: 1477-9560