Platelet adhesion in type 2 diabetes: impact of plasma albumin and mean platelet volume

Thrombosis Journal

Table 3 Relationship between mean platelet volume (MPV) and platelet adhesion at different conditions by Pearson correlation coefficients (Pearson r, P < 0.05 bold). Albumin surface (Alb); adenosine diphosphate (ADP); Adrenaline (Adr); Ristocetin (Ri); Collagen surface (Coll); Fibrinogen surface (Fib)

Surface + concentration of soluble activator	Healthy controls (n = 60)		Type 2 diabetic patients (n = 60)
Surface + concentration of soluble activator	Pearson r	P value	Pearson r	P value
Alb	-0,026	0,853	0,085	0,531
Alb + 0.1 µmol/L ADP	0,249	0,073	0,213	0,115
Alb + 1.0 µmol/L ADP	0,414	*0,002*	0,413	*0,002*
Alb + 10 µmol/L ADP	0,493	*< 0,001*	0,264	*0.049*
Alb + 0.1 µmol/L Adr	0,248	0,073	0,311	*0,021*
Alb + 1.0 µmol/L Adr	0,488	*< 0,001*	0,270	*0.046*
Alb + 0,1 mg/mL Ri	-0,093	0,571	0,031	0,820
Alb + 1,0 mg/mL Ri	0,039	0,778	0,024	0,861
Coll	0,417	*0,002*	0,395	*0,003*
Coll + 0.1 µmol/L ADP	0,451	*< 0,001*	0,390	*0,003*
Coll + 1.0 µmol/L ADP	0,444	*< 0,001*	0,385	*0,003*
Coll + 10 µmol/L ADP	0,327	*0,016*	0,333	*0,012*
Coll + 0.1 µmol/L Adr	0,418	*0,002*	0,371	*0,005*
Coll + 1.0 µmol/L Adr	0,413	*0,002*	0,346	*0,009*
Coll + 0,1 mg/mL Ri	0,434	*0,005*	0,285	*0.042*
Coll + 1,0 mg/mL Ri	0,186	0,179	0,111	0,415
Fib	0,338	*0,013*	0,330	*0,013*
Fib + 0.1 µmol/L ADP	0,433	*0,001*	0,344	*0,009*
Fib + 1.0 µmol/L ADP	0,492	*< 0,001*	0,394	*0,003*
Fib + 10 µmol/L ADP	0,384	*0,004*	0,356	*0,007*
Fib + 0.1 µmol/L Adr	0,389	*0,004*	-0,033	*0.081*
Fib + 1.0 µmol/L Adr	0,426	*0,001*	0,419	*0,001*
Fib + 0,1 mg/mL Ri	0,214	0,183	0,355	*0,010*
Fib + 1,0 mg/mL Ri	0,218	0,116	0,183	0,176

ISSN: 1477-9560