Point of care diagnostic of hypercoagulability and platelet function in COVID-19 induced acute respiratory distress syndrome: a retrospective observational study

Table 2 Clinical signs of hemostatic alterations (n = 18)

Parameters	Number of patients affected	Percentage of patients affected (n = 18 total)	Number of events total	Arithmetic mean of events per patient
Any form of hemostatic complication No evidence of hemostatic complication	14 4	78 % 22 %	34	2.4
Any form of bleeding event Major bleeding Clinically relevant non-major bleeding	10 3 8	56 % 17 % 44 %	15 3 12	1.5 1.0 1.2
Any form of thromboembolic event Deep vein/arm thrombosis Pulmonary embolism	9 7 4	50 % 39 % 22 %	19 13 6	2.1 1.1 1.5

Clinical signs of hemostatic alterations (total n=18) in course of ICU stay.
Hemostatic complications comprising bleeding events and thromboembolic events during intensive care for COVID-19. Bleeding events were assessed according to definitions by Schulman et al. [12] and Kaatz et al. [13]. Within the major bleeding group two patients had intracranial bleeding and one patient developed an extensive subcutaneous hematoma after central venous catheter placement. Thromboembolic events were included in the analysis in case they had been diagnosed by standardized ultrasound examinations or CT scans.

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