Table 2 Comparison of characteristics in APL patients with and without thrombosis
From: Risk factors of thrombosis in Chinese subjects with acute promyelocytic leukemia
Characteristics | APL patients with thrombosis(7) | APL patients without thrombosis(37) | P values |
|---|---|---|---|
Gender | |||
Female | 3 | 19 | 0.68 |
Male | 4 | 18 | 0.68 |
Age(years) | 42.3 | 40.9 | 0.823 |
WBC(×109/L) | 26.240 | 10.846 | 0.077 |
HGB(g/L) | 63.40 | 81.21 | 0.409 |
PLT(×109/L) | 15.60 | 33.71 | 0.334 |
Risk stratification | |||
Low-risk | 1 (14.3%) | 10 (27%) | 0.475 |
Intermediate-risk | 4 (57.1%) | 24 (64.9%) | 0.697 |
High-risk | 2 (28.6%) | 3 (8.1%) | 0.245 |
PML-RARα gene type | |||
Bcr1 | 2 (28.6%) | 26 (70.3%) | |
Bcr2 | 0 (0%) | 0 (0%) | |
Bcr3 | 5 (71.4%) | 10 (27.0%) | 0.027 |
Rare | 0 (0%) | 1 (2.7%) | |
Leukemic cell biomarks | |||
CD2 positive | 2 (28.6%) | 13 (35.1%) | 0.737 |
CD15 positive | 6 (85.7%) | 11 (29.7%) | 0.005 |
PAI-1 gene polymorphism | |||
4G4G | 5 (71.4%) | 3 (8.1%) | 0.0009 |
4G5G | 2 (28.6%) | 25 (67.6%) | |
5G5G | 0 (0%) | 9 (24.3%) | |
Differentiation syndrome | 2 (28.6%) | 7 (18.9%) | 0.562 |