Skip to main content

Table 2 Comparison of characteristics in APL patients with and without thrombosis

From: Risk factors of thrombosis in Chinese subjects with acute promyelocytic leukemia

Characteristics APL patients with thrombosis(7) APL patients without thrombosis(37) P values
Gender
 Female 3 19 0.68
 Male 4 18 0.68
Age(years) 42.3 40.9 0.823
 WBC(×109/L) 26.240 10.846 0.077
 HGB(g/L) 63.40 81.21 0.409
 PLT(×109/L) 15.60 33.71 0.334
Risk stratification
 Low-risk 1 (14.3%) 10 (27%) 0.475
 Intermediate-risk 4 (57.1%) 24 (64.9%) 0.697
 High-risk 2 (28.6%) 3 (8.1%) 0.245
PML-RARα gene type
 Bcr1 2 (28.6%) 26 (70.3%)  
 Bcr2 0 (0%) 0 (0%)  
 Bcr3 5 (71.4%) 10 (27.0%) 0.027
 Rare 0 (0%) 1 (2.7%)  
Leukemic cell biomarks
 CD2 positive 2 (28.6%) 13 (35.1%) 0.737
 CD15 positive 6 (85.7%) 11 (29.7%) 0.005
PAI-1 gene polymorphism
 4G4G 5 (71.4%) 3 (8.1%) 0.0009
 4G5G 2 (28.6%) 25 (67.6%)  
 5G5G 0 (0%) 9 (24.3%)  
 Differentiation syndrome 2 (28.6%) 7 (18.9%) 0.562