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Table 3 Comparison of gene mutation related to prognosis of APL patients with and without thrombosis

From: Risk factors of thrombosis in Chinese subjects with acute promyelocytic leukemia

Gene mutations

APL patients with thrombosis(7)

APL patients without thrombosis(37)

P values

WT-1

5 (71.4%)

9 (24.3%)

0.01

FLT3-ITD

6 (85.7%)

8 (21.6%)

0.0008

DNMT3A

0 (0%)

3 (8.1%)

0.44

TET2

2 (28.6%)

6 (16.2%)

0.43

IDH1

1 (14.3%)

3 (8.1%)

0.6

IDH2

0 (0%)

1 (2.7%)

0.66

NRAS

0 (0%)

1 (2.7%)

0.66

ASXL1

1 (14.3%)

6 (16.2%)

0.9

TP53

0 (0%)

0 (0%)

RUNX1

0 (0%)

0 (0%)

NPM1

0 (0%)

0 (0%)

CEBPA

0 (0%)

0 (0%)

C-kit

0 (0%)

0 (0%)

dupMLL

0 (0%)

0 (0%)