Table 2 Mean difference of coagulation factors among different lipid-lowering drugs users
| Â | Mean level | Mean difference (95% CI) | Adjusted mean difference a (95% CI) |
|---|---|---|---|
Fibrinogen, mg/dL | |||
 Fibrate/Niacin users (n = 21) | 294.4 ± 52.5 | Reference | Reference |
 All statin users (n = 1007) | 316.1 ± 68.4 | 21.6 (−7.8 to 51.1) | 19.1 (−10.0 to 48.2) |
 Rosuvastatin users (n = 104) | 316.3 ± 54.0 | 21.8 (−3.6 to 47.3) | 20.7 (−6.2 to 47.6) |
 Other statin users (n = 903) | 316.0 ± 69.9 | 21.6 (−8.5 to 51.7) | 18.6 (− 11.0 to 48.4) |
FVIII, IU/dL | |||
 Fibrate/Niacin users (n = 21) | 142.1 ± 34.4 | Reference | Reference |
 All statin users (n = 1008) | 130.5 ± 36.5 | −11.5 (− 27.3 to 4.2) | − 15.8 (−31.6 to 0.003) |
 Rosuvastatin users (n = 104) | 127.2 ± 33.1 | −14.8 (− 30.6 to 0.9) | − 17.6 (− 33.8 to − 1.3) |
 Other statin users (n = 904) | 130.9 ± 36.6 | −11.5 (− 27.1 to 4.7) | −15.5 (− 31.5 to 0.5) |
FIX, IU/dL | |||
 Fibrate/Niacin users (n = 21) | 136.5 ± 29.2 | Reference | Reference |
 All statin users (n = 1008) | 125.2 ± 27.6 | −11.2 (−23.2 to 0.7) | − 11.3 (− 23.2 to 0.4) |
 Rosuvastatin users (n = 104) | 122.4 ± 30.5 | − 14.1 (− 28.4 to 0.2) | − 14.9 (− 29.7 to − 0.08) |
 Other statin users (n = 904) | 125.6 ± 27.3 | −10.9 (− 22.7 to 0.9) | − 11.0 (− 22.7 to 0.7) |
FXI, IU/dL | |||
 Fibrate/Niacin users (n = 21) | 137.6 ± 28.0 | Reference | Reference |
 All statin users (n = 1008) | 120.4 ± 20.9 | −17.1 (− 30.0 to − 4.3) | −18.3 (− 27.3 to − 9.4) |
 Rosuvastatin users (n = 104) | 120.4 ± 18.4 | − 17.2 (− 26.8 to −7.5) | − 17.6 (− 27.4 to − 7.7) |
 Other statin users (n = 904) | 120.4 ± 21.2 | −17.1 (− 26.4 to − 7.9) | − 18.3 (− 27.4 to − 9.2) |