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Table 3 Comparative results of mean difference in coagulation profile among individuals using different lipid-lowering drugs

From: Differential effect of statin use on coagulation markers: an active comparative analysis in the NEO study

 

Adjusted mean differencea (95%CI)

Adjusted mean difference a (95% CI)

Adjusted mean difference a (95% CI)

Fibrinogen, mg/dL

 Fibrate/Niacin users

–

Reference

Reference

 Other statin users

Reference

–

18.6 (− 11.0 to 48.4)

 Rosuvastatin users

1.5 (−12.1 to 15.3)

–

20.7 (− 6.2 to 47.6)

 All statin users

–

19.1(− 10.0 to 48.2)

–

Factor VIII, IU/dL

 Fibrate/Niacin users

–

Reference

Reference

 Other statin users

Reference

–

− 15.5 (− 31.5 to 0.5)

 Rosuvastatin users

−2.6 (− 10.1 to 4.7)

–

− 17.6 (− 33.8 to −1.3)

 All statin users

–

− 15.8 (− 31.6 to 0.003)

–

Factor IX, IU/dL

 Fibrate/Niacin users

–

Reference

Reference

 Other statin users

Reference

–

− 11.0 (− 22.7 to 0.7)

 Rosuvastatin users

−2.3 (− 7.9 to 3.1)

–

− 14.9 (− 29.7 to − 0.08)

 All statin users

–

−11.3 (− 23.2 to 0.4)

–

Factor XI, IU/dL

 Fibrate/Niacin users

–

Reference

Reference

 Other statin users

Reference

–

−18.3 (− 27.4 to − 9.2)

 Rosuvastatin users

0.3 (−3.8 to 4.5)

–

−17.6 (− 27.4 to − 7.7)

 All statin users

–

− 18.3 (− 27.3 to − 9.4)

–

  1. CI confidence interval
  2. aadjusted for age, sex, body mass index, hypertension, smoking, diabetes, cardiovascular diseases