Fig. 2From: A thrombophilia family with protein S deficiency due to protein translation disorders caused by a Leu607Ser heterozygous mutation in PROS1Localization of protein S (PROS1). Localization of PROS1 mock, wild type (PROS1-WT), and the p.Leu607Ser mutation (PROS1-M) in HEK293T cells, as detected by immunofluorescence. There is no difference before and after introduction of the PROS1 1820T > C mutation. PROS1 expression was obviously downregulated after mutationBack to article page