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Table 5 Stratified Analysis of MACE at median Follow-up of 1.98 yr in all enrolled patients divided by the status of TCFA and level of rSS

From: Prognostic value of characteristics of plaque combined with residual syntax score among patients with STEMI undergoing primary PCI: an intravascular optical coherence tomography study

 

Status

Confounding factor category

Group = 0 (TCFA absent &Rss ≤ 4)

Group = 1 (TCFA present &Rss ≤ 4)

Group = 2 (TCFA absent &Rss>4)

Group = 3 (TCFA present &Rss>4)

P for trend

P for interaction

DM

 without

1(reference)

1.62 (0.64,4.1)

4.13 (1.35,12.61)

1.54 (1.06,2.26)

0.025*

0.226

 with

1(reference)

2.48 (0.43,14.38)

1.89 (0.36,10)

4.28 (0.75,24.44)

0.156

 

Age

 < media

1(reference)

2.93 (0.26,33.31)

0.86 (0.13,5.65)

6.88 (1.37,34.63)

0.088

0.490

 ≥ media

1(reference)

0.86 (0.21,3.54)

1.75 (0.68,4.46)

3.09 (0.97,9.83)

0.039

 

EF

 < 50%

1(reference)

3.69 (0.01,1086.65)

15.65 (0.22,1091.81)

21.82 (0.23,2112.96)

0.113

0.724

 ≥ 50%

1(reference)

0.83 (0.21,3.19)

1.33 (0.54,3.27)

3.25 (1.19,8.84)

0.037*

 

Smoke

 without

1(reference)

3.65 (0.49,27.06)

4.73 (1.07,20.9)

0.019*

0.191

 with

1(reference)

0.82 (0.16,4.11)

1.18 (0.43,3.24)

4.11 (1.51,11.19)

0.012*

 

Hypertension

 without

1(reference)

4.94 (1.48,16.5)

10.46 (1.94,56.45)

0.002*

0.012*

 with

1(reference)

1.08 (0.28,4.23)

0.33 (0.09,1.25)

2.01 (0.62,6.57)

0.826

 

History of PCI

 without

1(reference)

0.46 (0.06,3.73)

1.97 (0.84,4.6)

4.84 (1.82,12.88)

0.002*

0.192

 with

1(reference)

0.986

 

CRP

 < 10

1(reference)

1.76 (0.47,6.66)

1.47 (0.56,3.9)

6.06 (1.87,19.64)

0.017*

0.296

 ≥ 10

1(reference)

2.29 (0.46,11.5)

3.77 (0.59,23.96)

0.131

 

LPA

 < 300

1(reference)

0.92 (0.17,5.02)

1.54 (0.52,4.61)

7.42 (2.16,25.53)

0.006*

0.192

 ≥ 300

1(reference)

4.73 (0.69,32.42)

1.78 (0.5,6.37)

1.02 (0.21,4.94)

0.768

 

WBC

 < 10

1(reference)

3.8 (0.84,17.27)

2.15 (0.7,6.6)

8.37 (2.19,31.99)

0.011*

0.030*

 ≥ 10

1(reference)

2.02 (0.57,7.21)

6.53 (1.37,31.14)

0.027*

 

Plt

 < 300

1(reference)

0.85 (0.22,3.24)

1.34 (0.58,3.13)

4.02 (1.55,10.45)

0.013*

0.499

 ≥ 300

1(reference)

14.11 (0.51,388.76)

5.78 (0.11,300.43)

6.95 (0.11,451.72)

0.280

 

TMAO

 < media

1(reference)

0.72 (0.16,3.35)

4.09 (0.34,49.59)

0.848

0.474

 ≥ media

1(reference)

7.18 (0.89,58.24)

2.6 (0.42,16.11)

18.33 (2.92,115.1)

0.005*

 

Healing plaque

 without

1(reference)

0.85 (0.23,3.2)

1.55 (0.68,3.52)

5.6 (2.11,14.87)

0.004*

0.197

 with

1(reference)

0.580

 
  1. Confounding factors including sex, age, ejection fraction, smoke, hypertension, hyperlipidemia, diabetes mellitus, white blood cell, hemoglobin, platelet, creatine kinase, glucose, glycosylated hemoglobin, C-reactive protein
  2. TCFA thin-cap fibroatheroma, rSS residual syntax score, DM diabetes mellitus, EF ejection fraction, CRP, PCI percutaneous coronary intervention, CRP, C reactive protein, LPA lipse activator, WBC white blood cell, PLT platelet, TMAO trimethylamine N-oxide, Adj., adjusted
  3. MACE, major adverse cardiovascular events
  4. *P < 0.05