Table 2 Baseline characteristics of the 30-day survivors and early death group (died before 7 days)
Variable on admission | Normal reference ranges | 30-day Survivor (N = 13) | Died before 7 days (N = 11) | P value |
|---|---|---|---|---|
Age, years (SD) |  | 52 (±9) | 57 (±9) | 0.171 |
Female, n (%) | Â | 7 (54) | 1 (9) | 0.046 |
Comorbidities | ||||
 Hypertension, n (%) |  | 9 (69) | 7 (64) | 0.556 |
 Diabetes, n (%) |  | 8 (62) | 8 (73) | 0.444 |
 Overweight, (BMI > 25 kg/m2) n (%) |  | 2 (15) | 6 (55) | 0.055 |
 Obese, (BMI > 30 kg/m2) n (%) |  | 11 (85) | 2 (18) | 0.002 |
Disease Severity Scores | ||||
 SOFA score (IQR) |  | 4 (4–4) | 5 (4–7) | 0.360 |
 PaO2/FiO2 ratio (IQR) |  | 95 (60–103) | 101 (81–122) | 0.450 |
 DIC score (IQR) |  | 3 (2–3) | 3 (3–4) | 0.113 |
Laboratory Values | ||||
 Platelet count, × 109/L (IQR) | 171–388 | 352 (263–466) | 358 (255–438) | 0.776 |
 Urea, mmol/L (IQR) | 2.1–7.1 | 7.7 (5.8–8.5) | 9.3 (6.1–12.8) | 0.296 |
 Creatinine, μmol/L (IQR) | 64–104 | 67 (64–81) | 65 (56–136) | 0.943 |
 Prothrombin time, s (IQR)a | 11–12.5 | 13.3 (12.8–13.5) | 15.0 (13.6–15.8) | 0.013 |
 Activated partial thromboplastin time, s (IQR) | 25.1–36.5 | 29.9 (28.9–32.6) | 30.2 (28.7–33.3) | 0.809 |
 D-Dimer, mg/L (IQR) | < 0.25 | 0.9 (0.6–2.5) | 3.0 (0.9–5.3) | 0.096 |
 Fibrinogen, g/L (IQR) | 2–4 | 5 (5–5)b | 5 (5–5)b | 0.399 |
TEG Heparinase | ||||
 R time, min (IQR) | 4.3–8.3 | 7.7 (7.5–8.2) | 6.6 (5.4–9.7) | 0.579 |
 K time, min (IQR) | 0.8–1.9 | 1.1 (0.9–1.4) | 1.0 (0.8–2.0) | 0.830 |
 α-angle, degree (IQR) | 64–77 | 75.0 (71.3–78.9) | 77.3 (66.6–78.7) | 0.679 |
 Maximum amplitude, mm (IQR) | 52–68 | 71.1 (69.5–72.6) | 70.5 (69.1–71.7) | 0.503 |
 LY-30, % (IQR) | 0–8 | 0 (0–0.1) | 0 (0–0.6) | 0.529 |
TEG functional fibrinogen | ||||
 Maximum amplitude, mm (IQR) | 15–32 | 48.3 (41.4–50.4) | 42.1 (39.4–49.1) | 0.353 |