Fig. 2From: The disulfide bond Cys2724-Cys2774 in the C-terminal cystine knot domain of von Willebrand factor is critical for its dimerization and secretionIdentification of candidate VWF gene mutations. A Results of first-generation sequencing showed that one VWF allele of the proband had a c.8171G>A:p.C2724Y mutation in exon 51. B The location of the C2724Y mutation site in the CK domain of VWF molecularBack to article page