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Fig. 6 | Thrombosis Journal

Fig. 6

From: Agitation-dependent biomechanical forces modulate GPVI receptor expression and platelet adhesion capacity during storage

Fig. 6

Platelet adhesion and spreading over collagen matrix in manually mixed and agitated PCs during storage. A provides a demonstrative image characterizing platelets adhesion (marked with a red arrow) versus spreading (marked with a yellow arrow) on collagen matrix. B shows demonstrative images comparing different levels of platelet adhesion and spreading to collagen in one–day stored MM-PCs and CAG-PCs in presence and absence of PP2 treatment. Graph C compares number of adhered platelets among MM-PCs, CAG-PCs and PP2-treated CAG-PCs (n = 10) while D demonstrates different levels of platelet spreading on collagen matrix in each product during storage. CAG = continuously-agitated; MM = manually-mixed; .PC = platelet concentrate. Note: ns: not significant; *p < 0.05; **p < 0.01

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Thrombosis Journal

ISSN: 1477-9560

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