Fig. 8

Effects of TXA on red blood cells and platelets in orthopaedic surgery. The effects of TXA on red blood cell parameters as well as platelet counts were assessed, and a significantly reduced decrease in red blood cell count (A), haemoglobin levels (B) and haematocrit (C) at POD-1 could be observed. The mean corpuscular volume of red blood cells was also significantly increased at POD-1 in TXA-treated patients (D). A reduced decrease was also evident for platelet count at POD-1 in the TXA group (E). Data represent fold-change from preOP levels and are expressed as mean ± standard error of the mean. Placebo: n = 3, TXA: n = 15. *p = 0.05, 2-tailed Student t test. preOP: pre-operative, EOS: end of surgery, POD-1: post-operative day 1, POD-3: post-operative day 3