Variable | Number of patients | Univariate analysis | Multivariate analysis | ||||||
---|---|---|---|---|---|---|---|---|---|
VTE (-) | VTE ( +) | Odds ratio | 95% confidence interval | p-value | Odds ratio | 95% confidence interval | p-value | ||
Number of patients (n = 199) | 180 | 19 (9.5%) | |||||||
Diagnosis | Soft tissue sarcoma | 94 | 9 (8.7%) | ||||||
Bone sarcoma | 35 | 3 (7.9%) | |||||||
Metastasis | 41 | 5 (10.9%) | |||||||
Hematologic malignancy | 10 | 2 (16.7%) | |||||||
Sex | Male | 103 | 10 | ||||||
Female | 77 | 9 | 0.81 | 0.28–2.31 | 0.85a | ||||
Age (years) | 59.7 ± 1.4 | 70.8 ± 3.7 | |||||||
 < 60 | 74 | 2 | |||||||
≧ 60 | 106 | 17 | 5.89 | 1.33–54.1 | 0.011a | 5.80 | 1.32–26.5 | 0.021c | |
BMI (cm/kg) | 22.46 | 21.39 | 0.24b | ||||||
Size (mm) | 80.4 | 65.8 | 0.79b | ||||||
Location | Lower limb | 116 | 17 | ||||||
Other | 64 | 2 | 4.66 | 1.05–42.9 | 0.038a | 4.56 | 1.01–20.4 | 0.048c | |
Origin | Bone | 80 | 10 | ||||||
Soft | 100 | 9 | 0.72 | 0.25–2.08 | 0.63a | ||||
Subcutaneous ~ fascia | 36 | 4 | |||||||
Fascia ~ bone | 144 | 15 | 1.14 | 0.26–3.90 | 0.77a | ||||
D-dimer | 0.65 | 2.64 |  > 0.001b | 1.01 | 0.96–1.08 | 0.51c | |||
Performance Status | 0–2 | 154 | 16 | ||||||
3–4 | 26 | 3 | 1.11 | 0.19–4.29 | 0.74a | ||||
Pathological fracture | 23 | 3 | 1.28 | 0.22–4.99 | 0.71a | ||||
Hematologic status | Hemoglobin (g/dL) | 12.9 | 13 | 0.88b | |||||
White blood cell (/μL) | 7010 | 6080 | 0.38b | ||||||
Platelet (× 104/μL) | 28 | 26.2 | 0.99b | ||||||
C related protein (mg/L) | 1.78 | 0.56 | 0.80b |