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Table 1 Demographic and clinical variables for patients

From: Prevalence and risk factors of preoperative venous thromboembolism in patients with malignant musculoskeletal tumors: an analysis based on D-dimer screening and imaging

Variable Number of patients Univariate analysis Multivariate analysis
VTE (-) VTE ( +) Odds ratio 95% confidence interval p-value Odds ratio 95% confidence interval p-value
Number of patients (n = 199) 180 19 (9.5%)       
Diagnosis Soft tissue sarcoma 94 9 (8.7%)       
Bone sarcoma 35 3 (7.9%)       
Metastasis 41 5 (10.9%)       
Hematologic malignancy 10 2 (16.7%)       
Sex Male 103 10       
Female 77 9 0.81 0.28–2.31 0.85a    
Age (years)   59.7 ± 1.4 70.8 ± 3.7       
 < 60 74 2       
60 106 17 5.89 1.33–54.1 0.011a 5.80 1.32–26.5 0.021c
BMI (cm/kg)   22.46 21.39    0.24b    
Size (mm)   80.4 65.8    0.79b    
Location Lower limb 116 17       
Other 64 2 4.66 1.05–42.9 0.038a 4.56 1.01–20.4 0.048c
Origin Bone 80 10       
Soft 100 9 0.72 0.25–2.08 0.63a    
Subcutaneous ~ fascia 36 4       
Fascia ~ bone 144 15 1.14 0.26–3.90 0.77a    
D-dimer   0.65 2.64     > 0.001b 1.01 0.96–1.08 0.51c
Performance Status 0–2 154 16       
3–4 26 3 1.11 0.19–4.29 0.74a    
Pathological fracture 23 3 1.28 0.22–4.99 0.71a    
Hematologic status Hemoglobin (g/dL) 12.9 13    0.88b    
White blood cell (/μL) 7010 6080    0.38b    
Platelet (× 104/μL) 28 26.2    0.99b    
C related protein (mg/L) 1.78 0.56    0.80b    
  1. aFisher’s exact test
  2. bMann-Whitney U test
  3. cLogistic regression analysis