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Table 2 Univariable and Multivariable regression of risk factors for in-hospital bleeding events among patients with renal insufficiency (CCr < 60 ml/min)

From: LMWHs dosage and outcomes in acute pulmonary embolism with renal insufficiency, an analysis from a large real-world study

 

Univariable

Multivariable

Variable

OR and 95% Cl

P value

OR and 95% Cl

P value

Adjusted LMWH dose

0.52 (0.27–1.00)

0.0500

0.52 (0.27–1.00)

0.0496

Age > 80 (years)

1.08 (0.63–1.85)

0.7801

  

Female

1.04 (0.64–1.70)

0.8695

  

BMI, kg/m2

0.94 (0.87–1.01)

0.0933

  

Cancer

1.19 (0.53–2.69)

0.6762

1.36 (0.59–3.14)

0.4769

Pulse ≥ 110 bpm

0.62 (0.22–1.76)

0.3718

  

Anaemiaa

1.65 (1.00–2.75)

0.0523

  

Platelet < 100 × 109/L

1.21 (0.54–2.74)

0.6462

  

Length of hospital stay (days)

1.03 (1.02–1.06)

0.0005

1.03 (1.01–1.06)

0.0014

  1. OR and 95% CI were estimated by Logistic regression model
  2. Abbreviations: BMI body mass index, LMWH low molecular weight heparin, CCr creatinine clearance, OR odds ratio, 95% CI 95% confidence interval
  3. aAnemia refers to hemoglobin < 120 g/L for male and < 110 g/L for female, respectively