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Fig. 1 | Thrombosis Journal

Fig. 1

From: Use of thromboelastography before the administration of hemostatic agents to safely taper recombinant activated factor VII in acquired hemophilia A: a report of three cases

Fig. 1

Change in the reaction rate time (R) according to thromboelastography (TEG). The levels of factor VIII coagulant activity (FVIII:C) and the R-value according to TEG in three acquired hemophilia A patients (A-C) who were being treated with recombinant activated factor VII (rFVIIa) are shown. The doses of rFVIIa are also represented. The black line and dashed line represent dynamic changes in FVIII:C levels and the R-value, respectively. The x-axis indicates the number of days from the start of rFVIIa treatment until the FVIII:C level rose to > 20%. The day on which rFVIIa treatment was initiated was designated “day 1”. The horizontal dotted line indicates the R-value reference range (4.6-9.1 min) according to TEG. The administration of rFVIIa is indicated by grey boxes. “q3” means that rFVIIa was administered every 3 hours

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