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Table 2 Association between mortality and DIC scores, HMGB1, and histone H3

From: Prognostic value of plasma high mobility group box 1 protein and histone H3 levels in patients with disseminated intravascular coagulation: a multicenter prospective cohort study

Variables

Odds ratio (95% CI)

p-value*

DIC score (point)

1.28 (0.64 to 2.57)

0.48

HMGB1 (ng/mL)

1.02 (1.00 to 1.03)

0.02

Histone H3 (ng/mL)

1.02 (1.00 to 1.04)

0.04

Optimal cutoff point

  DIC score ≥ 6 point

1.58 (0.60 to 4.17)

0.36

  HMGB1 ≥ 8 (ng/mL)

5.47 (1.70 to 17.6)

0.004

  Histone H3 ≥ 2 (ng/mL)

9.07 (2.00 to 41.3)

0.004

  1. DIC disseminated intravascular coagulation, HMGB1 high mobility group box-1 protein
  2. * p-value is the null hypothesis that the odds ratio is equal to one