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Table 1 Study sample characteristics

From: Relationships between coagulation factors and thrombin generation in a general population with arterial and venous disease background

 

Reference group n = 1402

Arterial Disease group n = 502

Venous Disease group n = 195

Sex (females)

60.5% (848)

36.7% (184)

63.6% (124)

Age(years)

49.3 ± 9.8

63.8 ± 8.5

61.3 ± 10.1

BMI (kg/m2)

24.2 (22.2/26.3)

28.8 (25.7/32.2)

28.6 (25.5/31.5)

Cardiovascular risk factors

 Diabetes

0% (0)

20.1% (101)

9.7% (19)

 Obesity

0% (0)

41.2% (207)

36.9% (72)

 Smoking

22.5% (316)

16.2% (81)

11.3% (22)

 Arterial hypertension

0% (0)

72.5% (364)

59.0% (115)

 Dyslipidemia

0% (0)

40.1% (201)

30.8% (60)

Family history of MI/Stroke

31.1% (436)

43.6% (219)

43.6% (85)

Comorbidities

 CAD

0% (0)

46.5% (217)

9.1% (17)

 MI

0% (0)

30.4% (151)

5.2% (10)

 Stroke

0% (0)

18.5% (92)

6.2% (12)

 AF

0% (0)

9.2% (45)

6.2% (12)

 PAD

0% (0)

40.2% (200)

26.6% (51)

 CHF

0% (0)

6.2% (31)

6.7% (13)

 DVT

0% (0)

14.3% (71)

99.0% (193)

 PE

0% (0)

1.6% (8)

5.7% (11)

Therapy

 Anti-coagulant agentsa

1.8% (25)

61.0% (305)

35.4% (69)

 Oral contraceptive therapy

12.5% (174)

6.4% (32)

9.7% (19)

 Hormonal replacement therapy

5.5% (77)

5.6% (28)

11.3% (22)

  1. Abbreviations: BMI body mass index, MI myocardial infarction, AF atrial fibrillation, PAD peripheral artery disease, CAD coronary artery disease, CHF congestive heart failure, DVT deep venous thrombosis, PE pulmonary embolism
  2. aATC codes: B01AA (vitamin K antagonists), B01AB (heparin group), B01AE (direct thrombin inhibitors), B01AF (direct factor Xa inibitors), B01AX (other antithrombotic agents)