Table 2 Variable description according to PE diagnosis and in-hospital death occurrence

Patient (n)

292

109

322

79

Female sex (n (%))

98 (34)

36 (33)

104 (32)

30 (38)

Age (years)

68 ± 14

70 ± 11

67 ± 13

74 ± 10^c

Body mass index (Kg/m²)

28.4 ± 6.4

28.5 ± 6.1

28.7 ± 6.0

27.2 ± 7.2^a

Smoking history (n (%))

38 (13)

10 (9.2)

44 (14)

4 (5.1)

COVID-19 (WHO category) (n (%))

 • Mild/moderate

134 (46)

16 (15)^c

144 (45)

6 (7)^c

 • Severe

91 (31)

51 (47)^b

125 (39)

17 (22)^b

 • Critical

67 (23)

42 (39)^b

53 (17)

56 (71)^c

Comorbidities (n (%)):

 • Hypertension

164 (56)

57 (52)

168 (52)

53 (67)^a

 • Chronic kidney disease

76 (26)

34 (31)

91 (28)

19 (24)

 • Diabetes

60 (21)

21 (19)

62 (19)

19 (24)

 • Neoplasia

43 (15)

16 (15)

36 (11)

23 (29)^c

 • COPD

20 (6.8)

5 (4.6)

16 (5.0)

9 (11)

 • Autoimmune disease

16 (5.5)

7 (6.4)

16 (5.0)

7 (8.9)

 • Cirrhosis

16 (5.5)

4 (3.7)

13 (4.0)

7 (8.9)

 Pulmonary embolism (n (%))

-

-

79 (25)

30 (38)^a

 Intensive care unit admission (n (%))

33 (11)

41 (38)^c

40 (12)

34 (43)

 Orotracheal intubation (n (%))

29 (10)

35 (32)^c

31 (10)

33 (42)^c

 In-hospital death (n (%))

49 (17)

30 (32)^a

-

-

 Body temperature (°C)

36.8 ± 0.8

36.6 ± 0.7^a

36.8 ± 0.8

36.6 ± 0.7^a

 Respiratory rate (breaths per minute)

21 ± 5

21 ± 5

21 ± 5

23 ± 5c

 Arterial oxygen saturation (%)

96 [93–98]

94 [91–96]^c

95 [93–97]

94 [91–96]^b

 Systolic blood pressure (mm Hg)

135 ± 21

137 ± 22

135 ± 21

137 ± 20

 Heart rate (bpm)

83 ± 15

84 ± 14

82 ± 14

86 ± 18^a

 Hemoglobin (g/dl)

13.0 ± 1.9

13.0 ± 1.8

13.0 ± 1.8

12.8 ± 2.2

 WBC (cells × 10³/mm³)

6.74 [4.86–10.04]

8.78 [6.17–11.55]^c

6.84 [5.07–10.00]

9.90 [6.47–12.48]^c

 Lymphocytes (cells × 10³/mm³)

0.82 [0.58–1.10]

0.64 [0.43–0.93]

0.82 [0.54–1.10]

0.62 [0.38–0.92]^c

 Platelets (cells × 10³/mm³)

220 [168–299]

265 [209–345]^b

240 [182–325]

220 [165–295]

 CRP (mg/l)

62 [28–111]

66 [32–111]

58 [26–108]

81 [52–121]^c

 D-dimer (ng/ml FEU)

809 [480–2014]

1895 [788–5944]^c

899 [512–2504]

1555 [673–12300]^c

 eGFR (ml/min/1.73m²)

79 ± 32

78 ± 31

78 ± 32

81 ± 31

 ACEi/ARB (n (%))

104 (36)

35 (32)

110 (34)

29 (37)

 Statin (n (%))

70 (24)

18 (17)

66 (21)

22 (28)

 Antiplatelet (n (%))

65 (22)

20 (18)

62 (19)

23 (29)

 Any heparin use (n (%))

242 (83)

97 (89)

275 (85)

64 (81)