Table 1 Baseline characteristics of acute respiratory failure patients assisted with VV-ECMO
Total (n=70) | Survival Group (n=25) | Non-survival Group (n=45) | P-value | |
|---|---|---|---|---|
Male gender, (n%) | 43 (61.4) | 14 (56) | 29 (64.4) | 0.487 |
Age (y) | 43.51 ± 13.31 | 40.36 ± 13.43 | 45.27 ± 13.07 | 0.141 |
BMI (Kg/M2) | 24.49 ± 2.91 | 24.04 ± 2.21 | 24.74 ± 3.23 | 0.333 |
SOFA score | 7 (5–9.25) | 5 (4–6) | 8 (6.5–11) | 0.001 |
Primary disease or comorbidities, (n%) | 0.565 | |||
Polytrauma | 26 (37.1) | 9 (36) | 17 (37.8) | |
Respiratory tract hemorrhage | 10 (14.3) | 3 (12) | 7 (15.6) | |
Gastrointestinal hemorrhage | 20 (28.6) | 6 (24) | 14 (31.1) | |
Cardiovascular surgery | 8 (11.4) | 3 (12) | 5 (11.1) | |
Non-cardiovascular surgery | 6 (8.6) | 4 (16) | 2 (4.4) | |
Heparin free time, (min) | 102.34 ± 43.70 | 104.92 ± 48.01 | 100.91 ± 41.62 | 0.720 |
ECMO assisted time, (h) | 190.80 ± 88.95 | 188.60 ± 78.34 | 192.02 ± 95.17 | 0.880 |
Ventilation time, (h) | 279(214.75–432) | 360(144–480) | 268(220–354.5) | 0.730 |
tracheotomy, (n%) | 28 (40) | 12 (48) | 16 (35.6) | 0.323 |
Time in ICU, (d) | 19.30 ± 10.56 | 23.15 ± 10.72 | 17.16 ± 9.95 | 0.022 |
CRRT, (n%) | 36 (51.2) | 13 (52) | 23 (51.1) | 0.943 |
PaO2/FiO2 | 49.00 ± 7.17 | 54.01 ± 5.66 | 46.21 ± 6.41 | < 0.001 |
Baseline laboratory examinations | ||||
Creatine, (umol/L) | 86.7 (66.95–112.75) | 79 (59.5–88.5) | 94(74.5–130) | 0.002 |
Platelet count, (109/L) | 142.89 ± 49.56 | 163.2 ± 47.49 | 131.6 ± 47.50 | 0.010 |
Total bilirubin, (umol/L) | 13.85 (8.78–25.13) | 12 (8.9–22.5) | 14 (8.55–27) | 0.060 |
ACT, (s) | 101.51 ± 12.76 | 98.64 ± 12.08 | 103.11 ± 12.98 | 0.162 |
APTT, (s) | 34.08 ± 6.30 | 34.57 ± 8.13 | 33.8 ± 5.10 | 0.627 |
INR | 1.19 ± 0.32 | 1.15 ± 0.32 | 1.20 ± 0.32 | 0.513 |
D-dimer, (mg/L) | 2.65 (0.88–5.42) | 1.59 (0.45–4.81) | 3.18 (1.04–5.77) | 0.422 |
Fibrinogen, (g/L) | 4.09 ± 1.57 | 4.01 ± 1.44 | 4.14 ± 1.65 | 0.734 |
LDH, (U/L) | 820.63 ± 527.62 | 751.8 ± 455.17 | 858.87 ± 565.12 | 0.420 |