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Table 2 Thromboelastometric results of the different tests with edoxaban and apixaban. Data are presented as median and (Q1/Q3)

From: Modified thromboelastometric tests provide improved sensitivity and specificity to direct oral anticoagulants compared to standard thromboelastometric tests in-vitro

 

Apixaban

Edoxaban

0 ng/ml

31.25 ng/ml

62.5 ng/ml

125 ng/ml

250 ng/ml

500 ng/ml

0 ng/ml

31.25 ng/ml

62.5 ng/ml

125 ng/ml

250 ng/ml

500 ng/ml

CT NATEM

802 (678/875)

799 (701/882)

802 (761/955)

824 (694/925)

1006 (824/1110)

1017 (905/1085)

756 (574/875)

802 (586/886)

795 (719/969)

894 (737/1199)

1212 (995/1338)

1231 (1108/1405)

CT EXTEM

56 (52/63)

61 (59/67)

66 (61/72)

72 (69/75)

88 (81/97)

115 (98/129)

57 (56/62)

79 (76/80)

86 (84/90)

108 (102/120)

175 (148/202)

255 (215/284)

CT FIBTEM

57 (54/64)

59 (58/63)

64 (59/67)

69 (66/76)

83 (80/93)

114 (107/128)

54 (53/56)

73 (71/75)

87 (81/89)

106 (93/115)

176 (149/202)

245 (208/296)

CT HEPTEM

176 (173/210)

194 (184/202)

196 (192/201)

199 (186/214)

217 (198/224)

238 (219/246)

189 (182/196)

211 (200/216)

222 (195/230)

236 (228/247)

268 (258/280)

346 (326/359)

CT TFTEM

152 (117/177)

185 (157/209)

228 (173/286)

281 (256/303)

338 (324/386)

489 (419/522)

118 (106/136)

261 (215/293)

285 (274/350)

362 (334/413)

478 (425/509)

621 (588/680)

CT ECATEM

99 (92/108)

93 (88/109)

96 (89/104)

97 (87/100)

96 (89/104)

90 (86/95)

97 (92/101)

92 (84/97)

97 (89/101)

95 (87/97)

98 (94/103)

96 (86/102)

  1. CT Clotting time