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Table 3 Preliminary Reference Intervals (Median + 95% CI). Data based on samples without DOAC spiking

From: Modified thromboelastometric tests provide improved sensitivity and specificity to direct oral anticoagulants compared to standard thromboelastometric tests in-vitro

ROTEM test

N

CT [s]

CFT [s]

Alpha [˚]

A5 [mm]

A10 [mm]

A20 [mm]

MCF [mm]

LI30 [%]

maxV [mm/min]

maxV-t [s]

AUC [mm x min]

TFTEM

60

129 (119–135)

92 (84–104)

72 (70–74)

43 (41–44)

55 (53–56)

62 (59–63)

63 (61–64)

100 (100–100)

14 (12–15)

154 (148–175)

6219 (6110–6442)

ECATEM

60

97 (93–100)

79 (75–84)

74 (73–75)

47 (46–49)

58 (56–59)

64 (62–66)

64 (63–67)

100 (100–100)

17 (16–18)

136 (132–141)

6412 (6237–6671)

  1. CT Clotting time, CFT Clot formation time, MCF: A5/10/20 amplitude 5/10/20min after, CT maximum clot firmness; LI30 Lysis index after 30 min; AUC Area under the curve