Clinical/laboratory parameter | Day 1 of suspected HIT | Day 8 of suspected HIT | Test interpretation |
---|---|---|---|
4 T score | 6/8 | - | 0–3 low probability 4–5 intermediate probability 6–8 high probability |
HIT-IgG Acustar (U/ml) | 10.8 | 43.2 | < 1.0 U/ml |
HIT ELISA IgG (O.D.) (Immuncor, Waukesha, USA) | 1.465 | 2.902 | < 0.4 negative for anti-PF4 antibodies 0.4–1.0 weak positive for anti-PF4 antibodies > 1.0 positive for anti-PF4 antibodies |
HIPA (wells + out of 4) | 1/4 | 4/4 | ≤ 1/4 wells negative for HIT ≥ 2/4 wells positive for HIT |
HIPA interpretation | negative | positive | - |