Author ID | Country | Study design | Study population | Sample size | Follow up time | Mean or Median age in years | Service setting | Indication of warfarin |
---|---|---|---|---|---|---|---|---|
Salaheldin A, 2019 [32] | Sudan | Retrospective | Private cardiology clinic attendants | 21 | 14 months | Mean: 64, Median: 62 | Cardiology Clinic | AF, VHD, DVT, PE, LVT |
Karuri et al., 2019 [36] | Kenya | Retrospective | Adult outpatients | 406 | 2Â years and 6Â months | Mean: 42.7 (SD: 16.9) | Cardiac, hemato-oncology, and clinic | DVT, PE, Prosthetic valves, AF, VHD |
Sana et al., 2020 [43] | Tunisia | Prospective | AF patients ≥ 20 years | 915 | 12 months | Mean: 64.27 | In- and outpatients setting | AF |
Lauren et al., 2019Â [35] | Namibia | Retrospective | Adult outpatients | 215 | 12Â months | Median: 46 | Warfarin Clinic | DVT, PE, AF, CVA, AVR, LVT, DCM, MVR, DVR, Others |
Sonuga et al., 2016 [37] | South Africa | Retrospective | Adult patients | 136 | 6Â months | Mean: 62 (for male), Median: 66 (for female) | INR Clinic | VHD, mechanical heart valve replacement |
Fenta et al., 2017 [23] | Ethiopia | Retrospective | Adults outpatients | 360 | 12Â months | Mean: 35.3 | Cardiac and hematology clinics | AF, DVT, PE, VHD, MI, HVR, PVR |
Semakula et al., 2020 [5] | South Africa and Uganda | Retrospective | Outpatients | 229 | 6Â months | Median: 56 | Anti-coagulation clinic | VTE, AF, VHD |
Prinsloo et al., 2021 [38] | South Africa | Retrospective | Adult patients | 191 | 12Â months | Median: 56 | INR Clinic | AF, VTE, MPHV, APS, and LVT |
Ahmed et al., 2017 [41] | Sudan | Pre-and post- Intervention | Adult patients | 135 | 12Â months | Mean: 41.8 | Anticoagulation clinic | MVR, DVR, total valve replacement |
Botsile et al., 2020 [39] | Botswana | Retrospective | Patients aged ≥ 18 years | 142 | 5 months | Mean: 42 | INR Clinic | MHV replacement |
Masresha et al., 2021 [31] | Ethiopia | Retrospective | Adult outpatients | 202 | 2Â years | Mean: 44.33 | Outpatient department | AF, VHD, DVT, and PE |
Kizito et al., 2016Â [47] | Kenya | Prospective | Adult outpatients | 147 | NA | Mean: 41 | Hemato-oncology and cardiothoracic clinics | Heart disease, VTE, HVR |
Yimer et al., 2021[40] | Ethiopia | Retrospective | Adult outpatients | 300 | 2Â years | Mean: 56.4 | Anticoagulation Clinic | AF |
Sadhabiriss and Brown, 2021 [33] | South Africa | Retrospective | Adult outpatients | 263 | 1Â year | Mean age for AF patients: 64.68, mean age for PHV patients:41.83 | Outpatient adult medical department | non-valvular AF, PHV, venous thrombosis or embolism, arterial or left ventricle thrombus, valvular AF, HF |
Ntlokotsi et al., 2018 [28] | South Africa | Retrospective | Adult patients | 95 | 19Â years | Mean 39.7 (SD:18) | Academic hospital | HVR |
Rejeb et al., 2019 [29] | Tunisia | Retrospective | Adult patients | 200 | 3 years | Mean: 58.8 ± 12 | Cardiac clinic | AF |
Mwita et al., 2017 [30] | Botswana | Retrospective | Adult patients | 410 | 2 years | Median: 46(35–58 IQR) | Outpatient medical clinic | Mechanical valves, DVT, AF, intracardiac thrombosis, pulmonary hypertension |
Ebrahim et al., 2018 [7] | South Africa | Retrospective | Adult out patients | 363 | 6 years | Median: 55(IQR 44—64) | Warfarin anticoagulation Clinic | AF, VHD, PE VTE, SLE, hypercoagulable states |