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Fig. 1 | Thrombosis Journal

Fig. 1

From: Histopathologically TMA-like distribution of multiple organ thromboses following the initial dose of the BNT162b2 mRNA vaccine (Comirnaty, Pfizer/BioNTech): an autopsy case report

Fig. 1

Macroscopic and microscopic findings of the heart. a: Macroscopic haemorrhage in the posterior pericardium in situ at the autopsy. b: Gross findings of the heart after fixation. The cut surface of the heart after fixation shows black-red discoloration (arrowhead) in the entire circumference of the pericardium and pericardium-side myocardium. c: Scanning magnifications of the heart with haematoxylin-eosin (HE) staining. d: Schematic illustration of the microscopic pathology. The red dots indicate the microscopic haemorrhage, the blue rectangle indicates the thrombus, and the green arc indicates the contraction band necrosis. LV; left ventricle, IVS; interventricular septum, RV; right ventricle. e and f: Low- and high-power views of the haemorrhage in the cardiomyocytes. The haemorrhages were found in the pericardium and pericardium-side myocardium, which is compatible with the discolouration in macroscopic observation. Scale bars indicate 100 μm (e, f)

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