Table 2 Outcomes and blood transfusion between patients with and without coagulopathy
Variables | Total (n = 227) | No coagulopathy (n = 122) | Coagulopathy (n = 105) | P Value |
|---|---|---|---|---|
Outcomes | ||||
28-day death | 142 (63) | 59 (48) | 83 (79) | < 0.001 |
Causes of 28-day death (n = 142) | 0.602 | |||
Cardiovascular failure/futility | 15 (11) | 3 (5) | 12 (14) | |
Neurologic brain death declared | 59 (42) | 26 (44) | 33 (40) | |
Respiratory failure/futility | 4 (3) | 2 (3) | 2 (2) | |
Withdrawal for poor neurologic prognosis | 57 (40) | 24 (41) | 33 (40) | |
Withdrawal for other system failure | 2 (1) | 1 (2) | 1 (1) | |
Other | 2 (1) | 1 (2) | 1 (1) | |
Unknown | 3 (2) | 2 (3) | 1 (1) | |
POPC at hospital discharge | < 0.001 | |||
Good | 13 (6) | 12 (10) | 1 (1) | |
Mild Disability | 15 (7) | 10 (8) | 5 (5) | |
Moderate Disability | 7 (3) | 6 (5) | 1 (1) | |
Severe Disability | 26 (11) | 17 (14) | 9 (9) | |
Coma or vegetative state | 25 (11) | 18 (15) | 7 (7) | |
Death | 141 (62) | 59 (48) | 82 (78) | |
PCPC at hospital discharge | < 0.001 | |||
Normal | 19 (8) | 15 (12) | 4 (4) | |
Mild Disability | 11 (5) | 9 (7) | 2 (2) | |
Moderate Disability | 5 (2) | 4 (3) | 1 (1) | |
Severe Disability | 26 (11) | 17 (14) | 9 (9) | |
Coma or vegetative state | 25 (11) | 18 (15) | 7 (7) | |
Death | 141 (62) | 59 (48) | 82 (78) | |
Hospital length of stay | 7 (3, 21) | 8 (4, 28) | 5 (2, 12) | < 0.001 |
1-year death | 146 (64) | 61 (50) | 85 (81) | < 0.001 |
Alive with VABS-II score ≥ 70 at 1-year | 32 (15) | 26 (23) | 6 (6) | < 0.001 |
VABS status at 1-year (n = 217) | < 0.001 | |||
Death | 146 (67) | 61 (54) | 85 (83) | |
Profound disability (VABS-II < 45) | 26 (12) | 18 (16) | 8 (8) | |
Moderate to severe disability (VABS-II 45–69) | 13 (6) | 9 (8) | 4 (4) | |
Good functional status (VABS-II ≥ 70) | 32 (15) | 26 (23) | 6 (6) | |
Blood transfusion | ||||
Any blood product use | 119 (53) | 46 (38) | 73 (70) | < 0.001 |
Cryoprecipitate use | 17 (8) | 1 (1) | 16 (15) | < 0.001 |
FFP use | 66 (29) | 15 (12) | 51 (49) | < 0.001 |
Packed RBC | 92 (41) | 38 (31) | 54 (52) | 0.003 |
Platelet use | 22 (10) | 6 (5) | 16 (15) | 0.016 |