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Table 1 Baseline clinical characteristics

From: Efficacy and safety of oral anticoagulants in elderly patients with stable coronary artery disease and atrial fibrillation

Characteristics

Total

(n = 832)

with OAC

(n = 301)

without OAC

(n = 531)

P value

Age (mean ± SD)

78 ± 6.7

77 ± 6.1

78 ± 6.9

0.000

Female (n, %)

351(42.2)

135(44.9)

216(40.7)

0.244

BMI (mean ± SD)

24.7 ± 3.8

25.2 ± 3.5

24.3 ± 3.9

0.001

Comorbidity (n, %)

 Hypertension

630(75.7)

228(75.7)

402(75.7)

1.000

 Hyperlipidemia

171(20.6)

59(19.6)

112(21.1)

0.656

 Diabetes

227(27.3)

80(26.6)

147(27.7)

0.747

 Heart failure

307(36.9)

86(28.6)

221(41.6)

0.000

 Chronic obstructive pulmonary disease

38(4.6)

6(2.0)

32(6.0)

0.009

 Renal Insufficiency

121(14.5)

26(8.6)

95 (17.9)

0.000

 Chronic Renal Insufficiency

95(11.4)

20(6.6)

75(14.1)

0.001

 Malignant Tumor

116(13.9)

34(11.3)

82(15.4)

0.097

Type of atrial fibrillation (n, %)

 Paroxysmal

383(46.0)

128(42.5)

255(48.0)

0.129

 Persistent

178(21.4)

75(24.9)

103(19.4)

0.065

 Unclassified

271

98

173

 

History (n, %)

 Previous myocardial infarction

108(13.0)

20(6.6)

88(16.6)

0.000

 Previous stroke

211(25.4)

66(21.9)

145(27.3)

0.097

 Previous bleeding

32(3.8)

13(4.3)

19(3.6)

0.580

Concomitant medication (n, %)

 Statins

633(76.1)

252(83.7)

381(71.8)

0.000

 β-blockers

611(73.4)

238(79.1)

373(70.2)

0.006

 ACEI

200(24.0)

62(20.6)

138(26.0)

0.091

 ARB

349(41.9)

142(47.2)

207(39.0)

0.023

 Diuretics

475(57.1)

146(48.5)

329(62.0)

0.000

 Calcium Antagonists

448(53.8)

167(55.5)

281(52.9)

0.515

 PPI

217(26.1)

143(47.5)

204(38.4)

0.013

 APT

389(46.8)

159(52.8)

230(43.3)

0.009

  1. OAC Oral anticoagulant, SD Standard deviation, BMI Body mass index, ACEI Angiotensin converting enzyme inhibitors, ARB Angiotensin receptor blocker, PPI Proton pump inhibitors, APT Antiplatelet treatment