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Fig. 5 | Thrombosis Journal

Fig. 5

From: A snake venom-analog peptide that inhibits SARS-CoV-2 and papain-like protease displays antithrombotic activity in mice arterial thrombosis model, without interfering with bleeding time

Fig. 5

Effect of (p-BthTX-I)2 K on mice photochemical arterial thrombosis model. A Representative graph of the blood flow in the carotid artery of the groups of animals submitted to induction of arterial thrombosis by the photosensitizing method. In purple, the 0.9% NaCl group (n = 8). In red (n = 5) (p-BthTX-I)2 K 20.0 mg.kg− 1 group. Black, blue and green lines represent intermediate amounts of the peptide. B Box plot representing the carotid artery occlusion time of mice that received (p-BthTX-I)2 K at amounts from 1.75 mg/kg up to and 20.0 mg/kg (n = 5 animals each), and Vehicle (0.9% NaCl). Statistical analysis was performed using two-way ANOVA and multiple comparisons, with p < 0.01 being significant

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Thrombosis Journal

ISSN: 1477-9560

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