Table 2 Clinical outcomes according to liver fibrosis status

Low (N = 5639)

219 (3.9)

77 (1.4)

37 (0.7)

72 (1.3)

89 (1.6)

169 (3.0)

289 (5.1)

53 (0.9)

Intermediate (N = 656)

28 (4.3)

10 (1.5)

7 (1.1)

14 (2.1)

11 (1.7)

18 (2.7)

38 (5.8)

8 (1.2)

High (n = 91)

12 (13.2)

6 (6.6)

6 (6.6)

4 (4.4)

4 (4.4)

3 (3.3)

5 (5.5)

5 (5.5)

p value

< 0.001

< 0.001

< 0.001

0.011

0.108

0.922

0.76

< 0.001

Low (N = 3352)

112 (3.3)

31 (0.9)

18 (0.5)

37 (1.1)

54 (1.6)

94 (2.8)

182 (5.4)

30 (0.9)

Intermediate (N = 2666)

116 (4.4)

48 (1.8)

23 (0.9)

41 (1.5)

43 (1.6)

87 (3.3)

123 (4.6)

27 (1.0)

High (N = 368)

31 (8.4)

14 (3.8)

9 (2.4)

12 (3.3)

7 (1.9)

9 (2.4)

27 (7.3)

9 (2.4)

p value

< 0.001

< 0.001

< 0.001

0.003

0.913

0.481

0.06

0.02

Low (N = 763)

20 (2.6)

5 (0.7)

2 (0.3)

8 (1.0)

8 (1.0)

17 (2.2)

44 (5.8)

5 (0.7)

Intermediate (N = 4582)

188 (4.1)

58 (1.3)

32 (0.7)

66 (1.4)

83 (1.8)

135 (2.9)

242 (5.3)

45 (1.0)

High (N = 1041)

51 (4.9)

30 (2.9)

16 (1.5)

16 (1.5)

13 (1.2)

38 (3.7)

46 (4.4)

16 (1.5)

p value

0.051

< 0.001

0.005

0.648

0.174

0.209

0.397

0.152

NFS

Low (N = 3109)

92 (3.0)

33 (1.1)

17 (0.5)

33 (1.1)

37 (1.2)

86 (2.8)

157 (5.0)

24 (0.8)

Intermediate (N = 2842)

124 (4.4)

41 (1.4)

20 (0.7)

43 (1.5)

53 (1.9)

89 (3.1)

150 (5.3)

28 (1.0)

High (N = 435)

43 (9.9)

19 (4.4)

13 (3.0)

14 (3.2)

14 (3.2)

15 (3.4)

25 (5.7)

14 (3.2)

p value

< 0.001

< 0.001

< 0.001

0.001

0.003

0.592

0.802

< 0.001