Fig. 2From: The effect of recombinant versus plasma-derived von Willebrand factor on prolonged PFA closure times in ECMO patients with acquired von Willebrand syndrome – an observational studyEvaluation of the PFA-200 COL/ADP closure curves. The flow rate in µl/min is monitored until either complete closure occurs, the measurement exceeds 300 s or the sample volume runs out (which can happen in samples with a low hematocrit). In samples from ECMO-induced aVWS a sudden incline in flow can occur, as seen in the present example for the whole blood sample without VWF after approx. 270 sBack to article page