Variable | Coefficient | Stat | HR (95%CI) | P value |
---|---|---|---|---|
Age | 0.02 | 2.86 | 1.02(1.00,1.04) | 0.0909 |
BMI | 0.01 | 0.01 | 1.00(0.94,1.08) | 0.9029 |
Drinking | -0.35 | 2.10 | 0.70(0.44,1.13) | 0.1473 |
Smoking | -0.48 | 3.54 | 0.62(0.38,1.02) | 0.0599 |
Liver disease | ||||
āCirrhosis | -0.59 | 3.46 | 0.55(0.30,1.03) | 0.0628 |
āHepatic carcinoma | -0.32 | 0.81 | 0.73(0.37,1.45) | 0.3684 |
Comorbidities | ||||
āAtrial fibrillation | 0.67 | 2.04 | 1.95(0.78,4.88) | 0.1530 |
āCoronary heart disease | 0.41 | 1.29 | 1.50(0.75,3.02) | 0.2562 |
āCerebral infarction | 0.22 | 0.40 | 1.24(0.64,2.41) | 0.5257 |
āDiabetes | -0.19 | 0.61 | 0.83(0.52,1.33) | 0.4345 |
āAscites | -0.41 | 3.31 | 0.67(0.43,1.03) | 0.0687 |
āSplenomegaly | -0.34 | 2.37 | 0.71(0.47,1.10) | 0.1235 |
āCurrent GIB | -0.13 | 0.26 | 0.88(0.54,1.44) | 0.6126 |
āHistory of GIB | -0.34 | 1.82 | 0.71(0.44,1.17) | 0.1776 |
āHistory of abdominal surgery | 0.35 | 2.39 | 1.42(0.91,2.23) | 0.1218 |
āHistory of anticoagulants | 0.63 | 3.59 | 1.87(0.98,3.57) | 0.0580 |
āHistory of blood transfusion | -0.11 | 0.21 | 0.90(0.56,1.44) | 0.6501 |
āHistory of anti-hypertensive drugs | -0.29 | 0.39 | 0.75(0.30,1.86) | 0.5334 |
āHistory of endoscopic operation | 0.44 | 1.81 | 1.56(0.82,2.98) | 0.1781 |
āHistory of hepatic encephalopathy | -0.48 | 0.65 | 0.62(0.20,1.97) | 0.4197 |
āHistory of abdominal infection | -0.51 | 5.23 | 0.60(0.39,0.93) | 0.0222 |
The site of thrombus involvement | ||||
āMain portal vein thrombosis | -0.13 | 0.26 | 0.88(0.54,1.45) | 0.6112 |
āPortal branch thrombosis | -0.10 | 0.20 | 0.91(0.59,1.39) | 0.6514 |
āSMV thrombosis | -0.28 | 1.38 | 0.76(0.48,1.21) | 0.2405 |
āSplenic vein thrombosis | 0.17 | 0.39 | 1.18(0.70,1.99) | 0.5301 |
Esophageal varices | -0.44 | 3.38 | 0.64(0.40,1.03) | 0.0660 |
āRed color sign | -0.44 | 2.53 | 0.64(0.37,1.11) | 0.1117 |
Degree of esophageal varices | ||||
āmild | REF | Ā | Ā | Ā |
āmoderate | 0.20 | 0.20 | 1.22(0.51,2.94) | 0.6526 |
āsevere | 0.23 | 0.29 | 1.26(0.55,2.88) | 0.5896 |
CTP classification | ||||
āLevel A | REF | Ā | Ā | Ā |
āLevel B | -0.50 | 4.47 | 0.61(0.38,0.96) | 0.0345 |
āLevel C | -0.23 | 0.24 | 0.79(0.31,2.02) | 0.6276 |
Laboratory findings | ||||
āPTā>ā12.1(s) | -0.20 | 0.35 | 0.82(0.42,1.60) | 0.5554 |
āINRā>ā1.5 | 0.04 | 0.01 | 1.05(0.45,2.45) | 0.9174 |
āD-dimerā>ā0.55(mg/L) | 0.03 | 0.01 | 1.03(0.41,2.56) | 0.9490 |
āWBC (Ćā109/L) | ||||
āā<ā3.5 | -0.19 | 0.54 | 0.83(0.51,1.36) | 0.4616 |
āā>ā9.5 | -0.07 | 0.05 | 0.93(0.52,1.68) | 0.8172 |
RBCāā„ā3.8 (Ćā1012/L) | 0.41 | 3.26 | 1.51(0.97,2.37) | 0.0711 |
HBāā„ā115(g/L) | 0.49 | 4.68 | 1.64(1.05,2.56) | 0.0306 |
PLTāā„ā125 (Ćā109/L) | 0.21 | 0.90 | 1.23(0.80,1.89) | 0.3421 |
CRPā>ā5(mg/L) | -0.64 | 8.16 | 0.53(0.34,0.82) | 0.0043 |
ALBāā„ā40(g/L) | 0.65 | 6.39 | 1.91(1.16,3.15) | 0.0115 |
ALTā>ā40(U/L) | -0.25 | 0.71 | 0.78(0.44,1.39) | 0.3983 |
ASTā>ā35(U/L) | 0.41 | 3.40 | 1.51(0.97,2.34) | 0.0652 |
TBILā>ā21(Ī¼mol/L) | 0.13 | 0.35 | 1.14(0.74,1.77) | 0.5528 |
DBILā>ā10.2(Ī¼mol/L) | -0.05 | 0.06 | 0.95(0.61,1.47) | 0.8068 |
SCRā>ā92(Ī¼mol/L) | 0.01 | 0.01 | 1.00(0.56,1.78) | 0.9952 |
TGā>ā2.26(mmol/L) | -0.29 | 0.52 | 0.75(0.34,1.64) | 0.4719 |
HDLāā„ā1.15(mmol/L) | 0.10 | 0.20 | 1.11(0.71,1.73) | 0.6585 |
LDLā>ā2.16(mmol/L) | 0.08 | 0.15 | 1.09(0.71,1.67) | 0.7023 |
Kā<ā3.5(mmol/L) | 0.14 | 0.27 | 1.15(0.67,1.98) | 0.6043 |
AFPā>ā7(ng/mL) | 0.23 | 0.62 | 1.26(0.71,2.22) | 0.4307 |
Treatment and symptoms after diagnosis of PVT | ||||
āHepatic encephalopathy | -0.64 | 2.84 | 0.53(0.25,1.11) | 0.0919 |
āEndoscope ligation | 0.62 | 1.78 | 1.86(0.75,4.64) | 0.1825 |
āAbdominal infection | 0.22 | 0.35 | 1.25(0.60,2.59) | 0.5542 |
āBlood transfusion | -0.26 | 1.01 | 0.77(0.46,1.29) | 0.3161 |
āAbdominal surgery | 0.14 | 0.32 | 1.15(0.71,1.87) | 0.5732 |
āThrombolytic therapy | 0.55 | 6.34 | 1.73(1.13,2.66) | 0.0118 |
The drugs of thrombolytic therapy | ||||
āno drugs | REF | Ā | Ā | Ā |
āanticoagulants | 0.80 | 11.00 | 2.22(1.39,3.55) | 0.0009 |
āantiplatelets | 0.04 | 0.02 | 1.05(0.52,2.09) | 0.9017 |
Anticoagulant drugs | ||||
ālow molecular weight heparin | REF | Ā | Ā | Ā |
āwarfarin | 1.56 | 1.83 | 4.78(0.50,46.07) | 0.1760 |
Anticoagulant duration | 0.01 | 0.06 | 1.00(1.00,1.01) | 0.8009 |