| Whole Cohort (n = 48,066) |  | Hospitalized (n = 9,681) |  | ||
---|---|---|---|---|---|---|
 | Control (n = 47,187) | Anticoagulation (n = 879) | P-value | Control (n = 9,352) | Anticoagulation (n = 329) | P-value |
Age, yrs | 59.0 (43.0, 71.0) | 72.0 (67.0, 78.0) | < 0.01 | 69.0 (59.0, 76.0) | 73.0 (69.0, 80.0) | < 0.05 |
Race | ||||||
 White | 31616 (67.0) | 669 (76.1) | < 0.01 | 5472 (58.5) | 221 (67.2) | < 0.05 |
 Black | 14275 (30.3) | 196 (22.3) | 3646 (39.0) | 100 (30.4) | ||
 Other | 1296 (2.7) | 14 (1.6) | 234 (2.5) | 8 (2.4) | ||
Sex | ||||||
 Male | 38337 (81.2) | 855 (97.3) | < 0.01 | 8677 (92.8) | 319 (97.0) | < 0.05 |
Smoking | ||||||
 Current | 7115 (15.1) | 102 (11.6) | < 0.01 | 1657 (17.7) | 41 (12.5) | < 0.05 |
 Former | 10386 (22.0) | 343 (39.0) | 2738 (29.3) | 126 (38.3) | ||
 Never | 19163 (40.6) | 400 (45.5) | 4170 (44.6) | 143 (43.5) | ||
Comorbidities | ||||||
 HPL | 25277 (53.6) | 744 (84.6) | < 0.01 | 6513 (69.6) | 273 (83.0) | < 0.05 |
 COPD | 7560 (16.0) | 362 (41.2) | < 0.01 | 2710 (29.0) | 159 (48.3) | < 0.05 |
 CHF | 4715 (10.0) | 386 (43.9) | < 0.01 | 2107 (22.5) | 180 (54.7) | < 0.05 |
 CAD | 7205 (15.3) | 412 (46.9) | < 0.01 | 2592 (27.7) | 170 (51.7) | < 0.05 |
 MI | 2374 (5.0) | 145 (16.5) | < 0.01 | 1067 (11.4) | 80 (24.3) | < 0.05 |
 DM | 14819 (31.4) | 499 (56.8) | < 0.01 | 4546 (48.6) | 200 (60.8) | < 0.05 |
 HTN | 25710 (54.5) | 807 (91.8) | < 0.01 | 7200 (77.0) | 310 (94.2) | < 0.05 |
 PAD | 1939 (4.1) | 94 (10.7) | < 0.01 | 804 (8.6) | 42 (12.8) | < 0.05 |
 CAS | 1520 (3.2) | 94 (10.7) | < 0.01 | 587 (6.3) | 40 (12.2) | < 0.05 |
 CKD | 5442 (12.1) | 289 (32.9) | < 0.01 | 2461 (26.3) | 161 (48.9) | < 0.05 |
 AVR/MVR | 2194 (4.6) | 190 (21.6) | < 0.01 | 839 (9.0) | 91 (27.7) | < 0.05 |
 DVT | 1212 (2.6) | 158 (18.0) | < 0.01 | 518 (5.5) | 61 (18.5) | < 0.05 |
 PE | 612 (1.3) | 110 (12.5) | < 0.01 | 270 (2.9) | 54 (16.4) | < 0.05 |
 VTE | 1577 (3.3) | 222 (25.3) | < 0.01 | 671 (7.2) | 95 (28.9) | < 0.05 |
Medications | ||||||
 Aspirin | 3641 (7.7) | 116 (13.2) | < 0.01 | 1222 (13.1) | 60 (18.2) | < 0.05 |
 Insulin | 2976 (6.3) | 153 (17.4) | < 0.01 | 986 (10.5) | 66 (20.1) | < 0.05 |
 Statin | 10689 (22.7) | 536 (61.0) | < 0.01 | 2974 (31.8) | 194 (59.0) | < 0.05 |