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Table 2 Concentration of plasma edoxaban (ng/ml) during the study

From: Clinical trial assessing the safety of edoxaban with concomitant chemotherapy in patients with gynecological cancer-associated thrombosis (EGCAT study)

Time point

All patients (n = 16)

Cancer type

Edoxaban dosage

Ovarian (n = 12)

Uterus corpus (n = 4)

60 mg (n = 3)

30 mg (n = 13)

1

17.7 ± 10.9

14.9 ± 6.2

26.8 ± 16.6

15.6 ± 6.0

26.3 ± 22.4

2

216.6 ± 119.9

211.8 ± 93.2

229.9 ± 194.4

188.8 ± 78.2

330.4 ± 206.6

3

20.0 ± 15.6

15.2 ± 7.4

33.1 ± 25.2

16.0 ± 7.2

36.1 ± 30.4

4

257.1 ± 123.6

237.4 ± 82.5

311.3 ± 208.0

207.9 ± 68.8

453.7 ± 92.0

5

14.3 ± 7.8

12.8 ± 4.3

16.8 ± 12.7

11.9 ± 4.4

21.5 ± 13.9

6

222.4 ± 119.6

156.4 ± 53.4

332.3 ± 123.8

164.4 ± 51.6

396.5 ± 77.1

  1. All values are expressed as mean ± SD