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  1. Endothelial cell dysfunction, by promoting fibrin deposition, has been implicated in the development of multiple organ failure. Altered fibrinolysis during inflammation may participate in microvascular alterat...

    Authors: Karim Zouaoui Boudjeltia, Sandra Ollieuz, Michael Piagnerelli, Patrick Biston, Philippe Cauchie, Jean-Louis Vincent, Dany Brohee and Michel Vanhaeverbeek

    Citation: Thrombosis Journal 2009 7:10

    Content type: Original clinical investigation

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  2. The Azorean population presents the highest standardized mortality rate for cardiovascular diseases (CVD) when compared to mainland Portugal and other populations. Since thrombosis is a common cause of CVD, we...

    Authors: Claudia C Branco, Tânia Pereirinha, Rita Cabral, Paula R Pacheco and Luisa Mota-Vieira

    Citation: Thrombosis Journal 2009 7:9

    Content type: Original basic research

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  3. The aim of this case report is to describe control of Schamberg's disease using aminaphtone. We report on the case of a 28-year-old patient who presented with multiple purpuric lesions of the lower extremities...

    Authors: José Maria Pereira de Godoy and Fernando Batigália

    Citation: Thrombosis Journal 2009 7:8

    Content type: Case report

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  4. Every year, millions of people undergo percutaneous coronary intervention (PCI) with intracoronary stent implantation. A patient from the PRAGUE-8 trial (Optimal pre-PCI clopidogrel loading: 600 mg before ever...

    Authors: Zuzana Motovska, Petr Widimsky, Iuri Marinov, Robert Petr, Jaroslava Hajkova and Jan Kvasnicka

    Citation: Thrombosis Journal 2009 7:6

    Content type: Case report

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  5. A 27 year-old man who presented to the hospital with progressive lower extremity weakness, developed an acute ST elevation myocardial infarction on his second hospital day. Primary angioplasty to the left ante...

    Authors: Ayyash Melhem, Ankit Desai and Marion A Hofmann

    Citation: Thrombosis Journal 2009 7:5

    Content type: Case report

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  6. Dual anti-platelet therapy with aspirin and a thienopyridine (DAT) is used to prevent stent thrombosis after percutaneous coronary intervention (PCI). Low response to clopidogrel therapy (LR) occurs, but labor...

    Authors: Cosmo Godino, Loredana Mendolicchio, Filippo Figini, Azeem Latib, Andrew SP Sharp, John Cosgrave, Giliola Calori, Michela Cera, Alaide Chieffo, Alfredo Castelli, Attilio Maseri, Zaverio M Ruggeri and Antonio Colombo

    Citation: Thrombosis Journal 2009 7:4

    Content type: Original clinical investigation

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  7. Mild hypothermia is currently standard of care for cardiac arrest patients in many hospitals and a common belief is that hypothermia attenuates platelet aggregation. We wanted to examine the effects of clopido...

    Authors: Carl Högberg, David Erlinge and Oscar Ö Braun

    Citation: Thrombosis Journal 2009 7:2

    Content type: Original basic research

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  8. A 68-year-old woman presented with acute chest pain and a greatly increased platelet count. Cardiac catheterization revealed subtotal occlusion and a thrombus-like filling defect in the right coronary artery. ...

    Authors: Emin Alioglu, Nurullah Tuzun, Fahri Sahin, Buket Kosova, Serkan Saygi, Istemihan Tengiz, Ugur Turk, Nazan Ozsan and Ertugrul Ercan

    Citation: Thrombosis Journal 2009 7:1

    Content type: Case report

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  9. Disturbed cellular cholesterol homeostasis may lead to accumulation of cholesterol in human atheroma plaques. Cellular cholesterol homeostasis is controlled by the sterol regulatory element-binding transcripti...

    Authors: Yue-Mei Fan, Pekka J Karhunen, Mari Levula, Erkki Ilveskoski, Jussi Mikkelsson, Olli A Kajander, Otso Järvinen, Niku Oksala, Janita Thusberg, Mauno Vihinen, Juha-Pekka Salenius, Leena Kytömäki, Juhani T Soini, Reijo Laaksonen and Terho Lehtimäki

    Citation: Thrombosis Journal 2008 6:17

    Content type: Original clinical investigation

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  10. Anticoagulation with warfarin should be stopped 4–6 days before invasive procedures to avoid bleeding complications. Despite this routine, some patients still have high International Normalized Ratio (INR) val...

    Authors: Sam Schulman, Rajae Elbazi, Michelle Zondag and Martin O'Donnell

    Citation: Thrombosis Journal 2008 6:15

    Content type: Original clinical investigation

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  11. Increase in tissue factor (TF) and loss in thrombomodulin (TM) antigen levels has been described in various inflammatory disorders. The functional consequences of such changes in antigen concentrations in the ...

    Authors: Kim Frederix, Ingeborg M Kooter, René van Oerle, Diane Fens, Karly Hamulyak, Miriam E Gerlofs-Nijland, Hugo ten Cate and Henri MH Spronk

    Citation: Thrombosis Journal 2008 6:14

    Content type: Original basic research

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  12. To analyse the effects of rosiglitazone administered at different times on neointimal formation in hypercholesterolemic rabbits following vascular injury.

    Authors: Alexandre Alessi, Olímpio Ribeiro França Neto, Paulo Roberto Slud Brofman, Camila Prim, Lucia Noronha, Ruy Fernando Kuenzer Caetano Silva, Liz Andréa Villela Baroncini and Dalton Bertolim Précoma

    Citation: Thrombosis Journal 2008 6:12

    Content type: Original basic research

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  13. Although cigarette smoking is a well-established risk factor for vascular disease, the genetic mechanisms that link cigarette smoking to an increased incidence of stroke are not well understood. Genetic variat...

    Authors: John W Cole, David W Brown, Wayne H Giles, Oscar C Stine, Jeffrey R O'Connell, Braxton D Mitchell, John D Sorkin, Marcella A Wozniak, Barney J Stern, Mary J Sparks, Mark T Dobbins, Latasha T Shoffner, Nancy K Zappala, Laurie J Reinhart and Steven J Kittner

    Citation: Thrombosis Journal 2008 6:11

    Content type: Original clinical investigation

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  14. Venous thromboembolism (VTE) and thromboembolic arterial diseases are usually considered to be distinct entities, but there is evidence to suggest that these disorders may be linked. The aim of this study was ...

    Authors: Consuelo Huerta, Saga Johansson, Mari-Ann Wallander and Luis AGarcía Rodríguez

    Citation: Thrombosis Journal 2008 6:10

    Content type: Original clinical investigation

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  15. Heparin-induced thrombocytopenia type II (HIT II) is a rare immune-mediated complication of heparin. The diagnosis of HIT is considered in patients exposed to heparin, presenting with thrombocytopenia and thro...

    Authors: Eva Serasli, Maria Antoniadou, Venetia Tsara, Vassilis Kalpakidis, Angelos Megalopoulos, George Trellopoulos, Georgia Papaioannou and Pandora Christaki

    Citation: Thrombosis Journal 2008 6:9

    Content type: Case report

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  16. Neck of femur fractures predispose patients to venous thromboembolism (VTE). NICE has issued guideline 46 to reduce this risk through the use of antithrombic agents. We audited our department's VTE practise by...

    Authors: Radwane Faroug, Shireesha Konnuru, San S Min, Fazleenah Hussain and George Ampat

    Citation: Thrombosis Journal 2008 6:8

    Content type: Original clinical investigation

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  17. Warfarin treatment has a narrow therapeutic range, requiring meticulous monitoring and dosage titration. Individual dosage requirement has recently partly been explained by genetic variation of the warfarin me...

    Authors: Kari BenteFoss Haug, Mohammad N Sharikabad, Marianne K Kringen, Sigrid Narum, Stine T Sjaatil, Per Wiik Johansen, Peter Kierulf, Ingebjørg Seljeflot, Harald Arnesen and Odd Brørs

    Citation: Thrombosis Journal 2008 6:7

    Content type: Original clinical investigation

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  18. Atrial fibrillation affects an estimated 2.5 million Americans and incurs an average annual stroke risk of 4.5% per year. Despite warfarin reducing stroke risk by approximately 66%, prior studies show warfarin...

    Authors: Ajay Srivastava, Michael Hudson, Ihab Hamoud, Joao Cavalcante, Chetan Pai and Scott Kaatz

    Citation: Thrombosis Journal 2008 6:6

    Content type: Original clinical investigation

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  19. The relationship of D-dimer and deep-vein thrombosis (DVT) after total knee arthroplasty (TKA) remains controversial. The purpose of this study was to assess the value of D-dimer in the detection of early DVT ...

    Authors: Chung-Jen Chen, Ching-Jen Wang and Chung-Cheng Huang

    Citation: Thrombosis Journal 2008 6:5

    Content type: Original clinical investigation

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  20. The objective was to evaluate the effects of rosiglitazone on iliac arteries of hypercholesterolemic rabbits undergoing balloon catheter injury in the contralateral iliac arteries.

    Authors: Olímpio Ribeiro França Neto, Dalton Bertolim Precoma, Alexandre Alessi, Camila Prim, Ruy FernandoKuenzerCaetano da Silva, Lucia de Noronha and Liz AndréaVillela Baroncini

    Citation: Thrombosis Journal 2008 6:4

    Content type: Original basic research

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  21. To test the hypothesis that point-of-care assays of platelet reactivity would demonstrate reduced response to antiplatelet therapy in patients who experienced Drug Eluting Stent (DES) ST whilst on dual antipla...

    Authors: Alex R Hobson, Graham Petley, Geraint Morton, Keith D Dawkins and Nick P Curzen

    Citation: Thrombosis Journal 2008 6:1

    Content type: Original clinical investigation

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  22. To prospectively determine the role of platelet glycoprotein IIIa (GP IIIa) gene PlA1/PlA2 polymorphism on the long-term clinical outcome in patients with coronary artery disease undergoing coronary stenting.

    Authors: Claire Le Hello, Rémy Morello, Agnès Lequerrec, Christine Duarte, John Riddell and Martial Hamon

    Citation: Thrombosis Journal 2007 5:19

    Content type: Original clinical investigation

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  23. The true relationship between methylenetetrahydrofolate reductase C677T homozygosity and risk of recurrent spontaneous abortion is unknown, and it is unclear if women with these mutations should be anticoagula...

    Authors: Ivy Altomare, Alan Adler and Louis M Aledort

    Citation: Thrombosis Journal 2007 5:17

    Content type: Original clinical investigation

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  24. Influenza infections have been associated with procoagulant changes. Whether influenza infections lead to an increased risk of pulmonary embolism remains to be established.

    Authors: Matthijs van Wissen, Tymen T Keller, Brechje Ronkes, Victor EA Gerdes, Hans L Zaaijer, Eric CM van Gorp, Dees PM Brandjes, Marcel Levi and Harry R Büller

    Citation: Thrombosis Journal 2007 5:16

    Content type: Original clinical investigation

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  25. Although a number of studies have demonstrated the influence of ABO blood group on plasma levels of von Willebrand factor (VWF), the nature of this association and its clinical importance is still largely unkn...

    Authors: Massimo Franchini, Franco Capra, Giovanni Targher, Martina Montagnana and Giuseppe Lippi

    Citation: Thrombosis Journal 2007 5:14

    Content type: Review

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  26. During gram-negative sepsis, lipopolysaccharide (LPS) induces tissue factor expression on monocytes. The resulting disseminated intravascular coagulation leads to tissue ischemia and worsens the prognosis of s...

    Authors: Christoph Sucker, Kai Zacharowski, Matthias Thielmann and Matthias Hartmann

    Citation: Thrombosis Journal 2007 5:13

    Content type: Original clinical investigation

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  27. Oral anticoagulation compromises conventional lupus anticoagulant (LA) screening assays. Mixing studies can counteract the oral anticoagulant effect but the dilution reduces sensitivity and can generate false ...

    Authors: Gary W Moore

    Citation: Thrombosis Journal 2007 5:12

    Content type: Original basic research

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  28. Hyperhomocysteinemia has been described as a risk factor for unexplained recurrent pregnancy loss. Increased levels of homocysteine may be due to inadequate dietary intake of folate and vitamin B12 and inherit...

    Authors: Maristella D'Uva, Pierpaolo Di Micco, Ida Strina, Carlo Alviggi, Mariateresa Iannuzzo, Antonio Ranieri, Antonio Mollo and Giuseppe De Placido

    Citation: Thrombosis Journal 2007 5:10

    Content type: Original clinical investigation

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  29. Increased platelet reactivity has been implicated in cardiovascular disease – the major cause of death in patients with end stage renal disease (ESRD). FcGammaRIIA is a component of glycoprotein VI and Ib-IX-V...

    Authors: Feliciano A Serrano, Mohamed El-Shahawy, Richard J Solomon, Burton E Sobel and David J Schneider

    Citation: Thrombosis Journal 2007 5:7

    Content type: Original clinical investigation

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  30. Gender-related differences in incidence of arterial thrombosis have been a focus of interest for years. The platelet integrin αIIbβ3 is primarily responsible for the interaction between platelets and fibrinoge...

    Authors: Robert Loncar, Reiner B Zotz, Christoph Sucker, Aleksandar Vodovnik, Mario Mihalj and Rüdiger E Scharf

    Citation: Thrombosis Journal 2007 5:5

    Content type: Original basic research

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  31. Monitoring of antiplatelet therapy in patients at cardiovascular risk is difficult because existing platelet function tests are too sophisticated for clinical routine. The whole blood TEG® Platelet Mapping™ assay...

    Authors: Louise Bochsen, Bo Wiinberg, Mads Kjelgaard-Hansen, Daniel A Steinbrüchel and Pär I Johansson

    Citation: Thrombosis Journal 2007 5:3

    Content type: Original clinical investigation

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  32. Platelet adhesion and subsequent thrombus formation on a subendothelial matrix at the site of vascular damage play a crucial role in the arrest of posttraumatic bleeding but also in different pathological thro...

    Authors: Robert Loncar, Volker Stoldt, Sabine Hellmig, Rainer B Zotz, Mario Mihalj and Rüdiger E Scharf

    Citation: Thrombosis Journal 2007 5:2

    Content type: Original basic research

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  33. Recommendations for urgent reversal of oral anticoagulation with vitamin K1 antagonists are largely derived from case series employing empirical dosing regimens with vitamin K1 and prothrombin complex concentrate...

    Authors: Marzia Angelo, Bernhard Gutmann, Michele Adami, Bernd Zagler, Anton Zelger, Christoph Pechlaner and Christian J Wiedermann

    Citation: Thrombosis Journal 2007 5:1

    Content type: Case report

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  34. Benign Intracranial Hypertension (BIH) may be caused, at least in part, by intracranial sinus thrombosis. Thrombosis is normally due to derangements in blood coagulation cascade which may predispose to abnorma...

    Authors: Domenico De Lucia, Marisanta Napolitano, Pierpaolo Di Micco, Alferio Niglio, Andrea Fontanella and Giuseppe Di lorio

    Citation: Thrombosis Journal 2006 4:21

    Content type: Original clinical investigation

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  35. Thrombosis of the ovarian vein is a rare complication which arises classically in the postpartum. We report a case of 24-year-old woman with a history of Behçet's disease, who presented with pelvic and thoraci...

    Authors: Sonia Hammami, Mondher Golli, Faouzi Addad, Chiraz Hafsa, Amira Hamzaoui, Silvia Mahjoub and Amor Gannouni

    Citation: Thrombosis Journal 2006 4:20

    Content type: Case report

    Published on:

  36. Adhesion of platelets onto immobilized fibrinogen is of importance in initiation and development of thrombosis. According to a recent increase in evidence of a multiple biological property of antithrombin, we ...

    Authors: Robert Loncar, Uwe Kalina, Volker Stoldt, Volker Thomas, Rüdiger E Scharf and Aleksandar Vodovnik

    Citation: Thrombosis Journal 2006 4:19

    Content type: Original basic research

    Published on:

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  • Thrombosis Journal is the official journal of the Asian-Pacific Society on Thrombosis and Hemostasis.

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