Table 1 Demographic and clinical characteristics of the patients described

Case

1

2

3

Gender

F

F

F

Age

59

42

57

Cancer site

Ovarian (relapse)

Breast stage III-B

Ovarian stage IV

Time of catheter stay (days) before symptoms

1

155

63

Thrombus site

Superior vena cava

Superior vena cava extended to right atrium

Subclavian and yugular veins

Days of antimicrobials before thrombolysis

7

19

6

Indication for thrombolyis

Persitent fever and bacteremia.

Persistent fever and septic embolization

Persitent fever and septic embolization

Staphylococcus aureus methicillin sensible

+

+

+

Streptokinase dose

250,000 IU hr. bolus + 40,000 us/hr for 24 hrs.

250,000 IU us/hr bolus.

250,000 us 1 hr. bolus + 25,000 us/hr for 12 hrs.

Thrombus lysis

100%

100%

100%

ARDS*

No

No

No