Exposed | Non-exposed | Overall | Exp. vs. Non-exposed | ||||
---|---|---|---|---|---|---|---|
Exposed vs. non-exposed | WY | VTE incidence per 104 WY | WY | VTE incidence per 104 WY | WY | VTE incidence per 104 WY | IR (95% CI) |
Demographic data | |||||||
Age: 30+ years vs. <30 | 12,346 | 17.0 | 20,162 | 6.5 | 32,508 | 10.5 | 2.6 (1.3–5.7) |
BMI: 25+ vs. <25 | 8,764 | 17.1 | 23,696 | 8.0 | 32,460 | 10.5 | 2.1 (1.01–4.4) |
OC use: ever vs never | 30,388 | 10.5 | 2,116 | 9.5 | 32,504 | 10.5 | 1.1 (0.3–9.6) |
Other hormones: ever vs. never | 2,484 | 12.1 | 29,896 | 10.4 | 32,380 | 10.5 | 1.2 (0.2–3.7) |
Smoking: yes, ever | 16,878 | 10.7 | 15,615 | 10.2 | 32,493 | 10.5 | 1.04 (0.5–2.2) |
Medical history | |||||||
Personal history of VTE: yes | 318 | 125.8 | 32,190 | 9.3 | 32,508 | 10.5 | 13.5 (3.5–38.3) |
Family history of VTE: yes | 3,810 | 26.3 | 28,698 | 8.4 | 32,508 | 10,5 | 3.1 (1.3–6.8) |
Family history of varicous veins: yes | 14,764 | 15.6 | 17,744 | 6,2 | 32,508 | 10.5 | 2.5 (1.2–5.7) |
Family history of MI: yes | 3,919 | 20.4 | 28,589 | 9,1 | 32,508 | 10.5 | 2.2 (0.9–5.1) |
Family history of stroke: yes | 2,480 | 20.2 | 30,028 | 9,6 | 32,508 | 10.5 | 2.1 (0.6–5.5) |
Laboratory & genetic markers | |||||||
FVL mutation§: yes | 2,105 | 19.0 | 30,308 | 9.6 | 32,413 | 10.2 | 2.0 (0.5–5.7) |
Prothrombin mutation§: yes | 1,010 | 19.8 | 30,817 | 9.4 | 31,827 | 9.7 | 2.1 (0.24–8.3) |
Protein C deficiency#: yes | 1510 | 26.5 | 30,958 | 9.7 | 32,468 | 10.5 | 2.7 (0.7–7.8) |
AT deficiency#: yes | 1648 | 6.1 | 30,828 | 10.7 | 32,476 | 10.5 | 0.6 (0.01–3.4) |
MTHFR§: yes | 18,423 | 9.2 | 13,404 | 10.4 | 31,827 | 9.7 | 0.9 (0.4–1.9) |